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Atomistry » Fluorine » PDB 4zzj-5ah8 » 5a5j | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 4zzj-5ah8 » 5a5j » |
Fluorine in PDB 5a5j: Cytochrome 2C9 P450 Inhibitor ComplexEnzymatic activity of Cytochrome 2C9 P450 Inhibitor Complex
All present enzymatic activity of Cytochrome 2C9 P450 Inhibitor Complex:
1.14.99.38; Protein crystallography data
The structure of Cytochrome 2C9 P450 Inhibitor Complex, PDB code: 5a5j
was solved by
S.E.Skerratt,
M.J.De Groot,
C.Phillips,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5a5j:
The structure of Cytochrome 2C9 P450 Inhibitor Complex also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Cytochrome 2C9 P450 Inhibitor Complex
(pdb code 5a5j). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Cytochrome 2C9 P450 Inhibitor Complex, PDB code: 5a5j: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5a5jGo back to Fluorine Binding Sites List in 5a5j
Fluorine binding site 1 out
of 3 in the Cytochrome 2C9 P450 Inhibitor Complex
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 5a5jGo back to Fluorine Binding Sites List in 5a5j
Fluorine binding site 2 out
of 3 in the Cytochrome 2C9 P450 Inhibitor Complex
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 5a5jGo back to Fluorine Binding Sites List in 5a5j
Fluorine binding site 3 out
of 3 in the Cytochrome 2C9 P450 Inhibitor Complex
Mono view Stereo pair view
Reference:
S.E.Skerratt,
M.J.De Groot,
C.Phillips.
Discovery of A Novel Binding Pocket For Cyp 2C9 Inhibitors: Crystallography, Pharmacophore Modelling and Inhibitor Sar. To Be Published.
Page generated: Sun Dec 13 12:17:54 2020
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