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Atomistry » Fluorine » PDB 5aik-5avy » 5am7 » |
Fluorine in PDB 5am7: FGFR1 Mutant with An InhibitorEnzymatic activity of FGFR1 Mutant with An Inhibitor
All present enzymatic activity of FGFR1 Mutant with An Inhibitor:
2.7.10.1; Protein crystallography data
The structure of FGFR1 Mutant with An Inhibitor, PDB code: 5am7
was solved by
T.D.Bunney,
S.Wan,
N.Thiyagarajan,
L.Sutto,
S.V.Williams,
P.Ashford,
H.Koss,
M.A.Knowles,
F.L.Gervasio,
P.V.Coveney,
M.Katan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5am7:
The structure of FGFR1 Mutant with An Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the FGFR1 Mutant with An Inhibitor
(pdb code 5am7). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the FGFR1 Mutant with An Inhibitor, PDB code: 5am7: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5am7Go back to Fluorine Binding Sites List in 5am7
Fluorine binding site 1 out
of 2 in the FGFR1 Mutant with An Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5am7Go back to Fluorine Binding Sites List in 5am7
Fluorine binding site 2 out
of 2 in the FGFR1 Mutant with An Inhibitor
Mono view Stereo pair view
Reference:
T.Bunney,
S.Wan,
N.Thiyagarajan,
L.Sutto,
S.V.Williams,
P.Ashford,
H.Koss,
M.A.Knowles,
F.L.Gervasio,
P.V.Coveney,
M.Katan.
The Effect of Mutations on Drug Sensitivity and Kinase Activity of Fibroblast Growth Factor Receptors: A Combined Experimental and Theoretical Study Ebiomedicine 2015.
Page generated: Sun Dec 13 12:18:24 2020
ISSN: ESSN 2352-3964 DOI: 10.1016/J.EBIOM.2015.02.009 |
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