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Atomistry » Fluorine » PDB 5ci0-5dde » 5cp5 » |
Fluorine in PDB 5cp5: Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Benzo[Cd]Indol-2(1H)-One LigandProtein crystallography data
The structure of Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Benzo[Cd]Indol-2(1H)-One Ligand, PDB code: 5cp5
was solved by
Y.Zhang,
M.Song,
Z.Liu,
X.Xue,
Y.Xu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Benzo[Cd]Indol-2(1H)-One Ligand
(pdb code 5cp5). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Benzo[Cd]Indol-2(1H)-One Ligand, PDB code: 5cp5: Fluorine binding site 1 out of 1 in 5cp5Go back to Fluorine Binding Sites List in 5cp5
Fluorine binding site 1 out
of 1 in the Crystal Structure of the First Bromodomain of Human BRD4 in Complex with Benzo[Cd]Indol-2(1H)-One Ligand
Mono view Stereo pair view
Reference:
X.Xue,
Y.Zhang,
Z.Liu,
M.Song,
Y.Xing,
Q.Xiang,
Z.Wang,
Z.Tu,
Y.Zhou,
K.Ding,
Y.Xu.
Discovery of Benzo[Cd]Indol-2(1H)-Ones As Potent and Specific Bet Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation J.Med.Chem. V. 59 1565 2016.
Page generated: Sun Dec 13 12:20:22 2020
ISSN: ISSN 0022-2623 PubMed: 26731490 DOI: 10.1021/ACS.JMEDCHEM.5B01511 |
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