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Atomistry » Fluorine » PDB 5ddf-5dy7 » 5drb | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5ddf-5dy7 » 5drb » |
Fluorine in PDB 5drb: Crystal Structure of WNK1 in Complex with WNK463Enzymatic activity of Crystal Structure of WNK1 in Complex with WNK463
All present enzymatic activity of Crystal Structure of WNK1 in Complex with WNK463:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of WNK1 in Complex with WNK463, PDB code: 5drb
was solved by
D.Kohls,
X.Xie,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of WNK1 in Complex with WNK463
(pdb code 5drb). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of WNK1 in Complex with WNK463, PDB code: 5drb: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5drbGo back to Fluorine Binding Sites List in 5drb
Fluorine binding site 1 out
of 3 in the Crystal Structure of WNK1 in Complex with WNK463
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 5drbGo back to Fluorine Binding Sites List in 5drb
Fluorine binding site 2 out
of 3 in the Crystal Structure of WNK1 in Complex with WNK463
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 5drbGo back to Fluorine Binding Sites List in 5drb
Fluorine binding site 3 out
of 3 in the Crystal Structure of WNK1 in Complex with WNK463
Mono view Stereo pair view
Reference:
K.Yamada,
H.M.Park,
D.F.Rigel,
K.Dipetrillo,
E.J.Whalen,
A.Anisowicz,
M.Beil,
J.Berstler,
C.E.Brocklehurst,
D.A.Burdick,
S.L.Caplan,
M.P.Capparelli,
G.Chen,
W.Chen,
B.Dale,
L.Deng,
F.Fu,
N.Hamamatsu,
K.Harasaki,
T.Herr,
P.Hoffmann,
Q.Y.Hu,
W.J.Huang,
N.Idamakanti,
H.Imase,
Y.Iwaki,
M.Jain,
J.Jeyaseelan,
M.Kato,
V.K.Kaushik,
D.Kohls,
V.Kunjathoor,
D.Lasala,
J.Lee,
J.Liu,
Y.Luo,
F.Ma,
R.Mo,
S.Mowbray,
M.Mogi,
F.Ossola,
P.Pandey,
S.J.Patel,
S.Raghavan,
B.Salem,
Y.H.Shanado,
G.M.Trakshel,
G.Turner,
H.Wakai,
C.Wang,
S.Weldon,
J.B.Wielicki,
X.Xie,
L.Xu,
Y.I.Yagi,
K.Yasoshima,
J.Yin,
D.Yowe,
J.H.Zhang,
G.Zheng,
L.Monovich.
Small-Molecule Wnk Inhibition Regulates Cardiovascular and Renal Function. Nat.Chem.Biol. V. 12 896 2016.
Page generated: Sun Dec 13 12:21:05 2020
ISSN: ESSN 1552-4469 PubMed: 27595330 DOI: 10.1038/NCHEMBIO.2168 |
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