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Atomistry » Fluorine » PDB 5dz3-5ese » 5eqg » |
Fluorine in PDB 5eqg: Mfs Transporter in Complex with Inhibitor (2~{S})-3-(4-Fluorophenyl)- 2-[2-(3-Hydroxyphenyl)Ethanoylamino]-~{N}-[(1~{S})-1- Phenylethyl]PropanamideProtein crystallography data
The structure of Mfs Transporter in Complex with Inhibitor (2~{S})-3-(4-Fluorophenyl)- 2-[2-(3-Hydroxyphenyl)Ethanoylamino]-~{N}-[(1~{S})-1- Phenylethyl]Propanamide, PDB code: 5eqg
was solved by
K.Kapoor,
J.Finer-Moore,
B.P.Pedersen,
L.Caboni,
A.B.Waight,
R.Hillig,
P.Bringmann,
I.Heisler,
T.Muller,
H.Siebeneicher,
R.M.Stroud,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Mfs Transporter in Complex with Inhibitor (2~{S})-3-(4-Fluorophenyl)- 2-[2-(3-Hydroxyphenyl)Ethanoylamino]-~{N}-[(1~{S})-1- Phenylethyl]Propanamide
(pdb code 5eqg). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Mfs Transporter in Complex with Inhibitor (2~{S})-3-(4-Fluorophenyl)- 2-[2-(3-Hydroxyphenyl)Ethanoylamino]-~{N}-[(1~{S})-1- Phenylethyl]Propanamide, PDB code: 5eqg: Fluorine binding site 1 out of 1 in 5eqgGo back to Fluorine Binding Sites List in 5eqg
Fluorine binding site 1 out
of 1 in the Mfs Transporter in Complex with Inhibitor (2~{S})-3-(4-Fluorophenyl)- 2-[2-(3-Hydroxyphenyl)Ethanoylamino]-~{N}-[(1~{S})-1- Phenylethyl]Propanamide
Mono view Stereo pair view
Reference:
K.Kapoor,
J.S.Finer-Moore,
B.P.Pedersen,
L.Caboni,
A.Waight,
R.C.Hillig,
P.Bringmann,
I.Heisler,
T.Muller,
H.Siebeneicher,
R.M.Stroud.
Mechanism of Inhibition of Human Glucose Transporter GLUT1 Is Conserved Between Cytochalasin B and Phenylalanine Amides. Proc.Natl.Acad.Sci.Usa V. 113 4711 2016.
Page generated: Sun Dec 13 12:21:46 2020
ISSN: ESSN 1091-6490 PubMed: 27078104 DOI: 10.1073/PNAS.1603735113 |
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