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Atomistry » Fluorine » PDB 5esf-5fct » 5etr » |
Fluorine in PDB 5etr: S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom ResolutionEnzymatic activity of S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution
All present enzymatic activity of S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution:
2.7.6.3; Protein crystallography data
The structure of S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution, PDB code: 5etr
was solved by
M.L.Dennis,
T.S.Peat,
J.D.Swarbrick,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5etr:
The structure of S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution
(pdb code 5etr). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution, PDB code: 5etr: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5etrGo back to Fluorine Binding Sites List in 5etr
Fluorine binding site 1 out
of 2 in the S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5etrGo back to Fluorine Binding Sites List in 5etr
Fluorine binding site 2 out
of 2 in the S. Aureus 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase Complexed with Ampcpp and Inhibitor at 1.32 Angstrom Resolution
Mono view Stereo pair view
Reference:
M.L.Dennis,
N.P.Pitcher,
M.D.Lee,
A.J.Debono,
Z.C.Wang,
J.R.Harjani,
R.Rahmani,
B.Cleary,
T.S.Peat,
J.B.Baell,
J.D.Swarbrick.
Structural Basis For the Selective Binding of Inhibitors to 6-Hydroxymethyl-7,8-Dihydropterin Pyrophosphokinase From Staphylococcus Aureus and Escherichia Coli. J.Med.Chem. V. 59 5248 2016.
Page generated: Thu Aug 1 09:14:21 2024
ISSN: ISSN 0022-2623 PubMed: 27094768 DOI: 10.1021/ACS.JMEDCHEM.6B00002 |
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