|
Atomistry » Fluorine » PDB 5fd2-5g3j » 5fdp | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5fd2-5g3j » 5fdp » |
Fluorine in PDB 5fdp: Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.Enzymatic activity of Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.
All present enzymatic activity of Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.:
2.7.10.1; Protein crystallography data
The structure of Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution., PDB code: 5fdp
was solved by
S.G.Bartual,
D.M.Pinkas,
Z.Wang,
K.Ding,
P.Mahajan,
K.Kupinska,
S.Mukhopadhyay,
C.Strain-Damerell,
O.Borkowska,
R.Talon,
J.Kopec,
E.Williams,
C.Tallant,
A.Chaikuad,
F.Sorell,
J.Newman,
N.Burgess-Brown,
C.H.Arrowsmith,
F.Von Delft,
A.M.Edwards,
C.Bountra,
A.Bullock,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.
(pdb code 5fdp). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution., PDB code: 5fdp: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5fdpGo back to Fluorine Binding Sites List in 5fdp
Fluorine binding site 1 out
of 3 in the Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 5fdpGo back to Fluorine Binding Sites List in 5fdp
Fluorine binding site 2 out
of 3 in the Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 5fdpGo back to Fluorine Binding Sites List in 5fdp
Fluorine binding site 3 out
of 3 in the Structure of DDR1 Receptor Tyrosine Kinase in Complex with D2099 Inhibitor at 2.25 Angstroms Resolution.
Mono view Stereo pair view
Reference:
Z.Wang,
H.Bian,
S.G.Bartual,
W.Du,
J.Luo,
H.Zhao,
S.Zhang,
C.Mo,
Y.Zhou,
Y.Xu,
Z.Tu,
X.Ren,
X.Lu,
R.A.Brekken,
L.Yao,
A.N.Bullock,
J.Su,
K.Ding.
Structure-Based Design of Tetrahydroisoquinoline-7-Carboxamides As Selective Discoidin Domain Receptor 1 (DDR1) Inhibitors. J.Med.Chem. V. 59 5911 2016.
Page generated: Sun Dec 13 12:22:22 2020
ISSN: ISSN 0022-2623 PubMed: 27219676 DOI: 10.1021/ACS.JMEDCHEM.6B00140 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |