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Atomistry » Fluorine » PDB 5ifd-5j82 » 5j2q | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5ifd-5j82 » 5j2q » |
Fluorine in PDB 5j2q: Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) SiteProtein crystallography data
The structure of Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) Site, PDB code: 5j2q
was solved by
Z.L.Salie,
K.A.Kirby,
S.G.Sarafianos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5j2q:
The structure of Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) Site also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) Site
(pdb code 5j2q). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) Site, PDB code: 5j2q: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5j2qGo back to Fluorine Binding Sites List in 5j2q
Fluorine binding site 1 out
of 2 in the Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) Site
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5j2qGo back to Fluorine Binding Sites List in 5j2q
Fluorine binding site 2 out
of 2 in the Hiv-1 Reverse Transcriptase in Complex with Dna That Has Incorporated A Mismatched Efda-Mp at the N-(Pre-Translocation) Site
Mono view Stereo pair view
Reference:
Z.L.Salie,
K.A.Kirby,
E.Michailidis,
B.Marchand,
K.Singh,
L.C.Rohan,
E.N.Kodama,
H.Mitsuya,
M.A.Parniak,
S.G.Sarafianos.
Structural Basis of Hiv Inhibition By Translocation-Defective Rt Inhibitor 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine (Efda). Proc.Natl.Acad.Sci.Usa V. 113 9274 2016.
Page generated: Thu Aug 1 10:23:24 2024
ISSN: ESSN 1091-6490 PubMed: 27489345 DOI: 10.1073/PNAS.1605223113 |
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