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Atomistry » Fluorine » PDB 5j8m-5jw1 » 5jfr | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5j8m-5jw1 » 5jfr » |
Fluorine in PDB 5jfr: Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug DiscoveryEnzymatic activity of Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery
All present enzymatic activity of Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery:
3.4.11.18; Protein crystallography data
The structure of Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery, PDB code: 5jfr
was solved by
D.R.Dougan,
J.D.Lawson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5jfr:
The structure of Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery
(pdb code 5jfr). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery, PDB code: 5jfr: Fluorine binding site 1 out of 1 in 5jfrGo back to Fluorine Binding Sites List in 5jfr
Fluorine binding site 1 out
of 1 in the Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery
Mono view Stereo pair view
Reference:
C.Mcbride,
Z.Cheruvallath,
M.Komandla,
M.Tang,
P.Farrell,
J.D.Lawson,
D.Vanderpool,
Y.Wu,
D.R.Dougan,
A.Plonowski,
C.Holub,
C.Larson.
Discovery of Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery and Structure Based Drug Design-Part 2. Bioorg.Med.Chem.Lett. V. 26 2779 2016.
Page generated: Sun Dec 13 12:25:21 2020
ISSN: ESSN 1464-3405 PubMed: 27136719 DOI: 10.1016/J.BMCL.2016.04.072 |
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