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Atomistry » Fluorine » PDB 5j8m-5jw1 » 5jfs | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5j8m-5jw1 » 5jfs » |
Fluorine in PDB 5jfs: Crystal Structure of Trka in Complex with Pf-00593174Enzymatic activity of Crystal Structure of Trka in Complex with Pf-00593174
All present enzymatic activity of Crystal Structure of Trka in Complex with Pf-00593174:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of Trka in Complex with Pf-00593174, PDB code: 5jfs
was solved by
J.Jayasankar,
D.Brown,
S.Skerratt,
R.Kurumbail,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Trka in Complex with Pf-00593174
(pdb code 5jfs). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Trka in Complex with Pf-00593174, PDB code: 5jfs: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5jfsGo back to Fluorine Binding Sites List in 5jfs
Fluorine binding site 1 out
of 2 in the Crystal Structure of Trka in Complex with Pf-00593174
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5jfsGo back to Fluorine Binding Sites List in 5jfs
Fluorine binding site 2 out
of 2 in the Crystal Structure of Trka in Complex with Pf-00593174
Mono view Stereo pair view
Reference:
S.E.Skerratt,
M.Andrews,
S.K.Bagal,
J.Bilsland,
D.Brown,
P.J.Bungay,
S.Cole,
K.R.Gibson,
R.Jones,
I.Morao,
A.Nedderman,
K.Omoto,
C.Robinson,
T.Ryckmans,
K.Skinner,
P.Stupple,
G.Waldron.
The Discovery of A Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (Pf-06273340) For the Treatment of Pain. J. Med. Chem. V. 59 10084 2016.
Page generated: Thu Aug 1 10:31:40 2024
ISSN: ISSN 1520-4804 PubMed: 27766865 DOI: 10.1021/ACS.JMEDCHEM.6B00850 |
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