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Fluorine in PDB 5jvz: Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 MutantEnzymatic activity of Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant
All present enzymatic activity of Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant:
1.14.99.1; Protein crystallography data
The structure of Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant, PDB code: 5jvz
was solved by
M.G.Malkowski,
B.J.Orlando,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5jvz:
The structure of Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant
(pdb code 5jvz). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant, PDB code: 5jvz: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5jvzGo back to Fluorine Binding Sites List in 5jvz
Fluorine binding site 1 out
of 2 in the Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5jvzGo back to Fluorine Binding Sites List in 5jvz
Fluorine binding site 2 out
of 2 in the Crystal Structure of Flurbiprofen Bound to S121P Murine Cox-2 Mutant
Mono view Stereo pair view
Reference:
L.Dong,
C.Yuan,
B.J.Orlando,
M.G.Malkowski,
W.L.Smith.
Fatty Acid Binding to the Allosteric Subunit of Cyclooxygenase-2 Relieves A Tonic Inhibition of the Catalytic Subunit. J.Biol.Chem. V. 291 25641 2016.
Page generated: Sun Dec 13 12:25:53 2020
ISSN: ESSN 1083-351X PubMed: 27756840 DOI: 10.1074/JBC.M116.757310 |
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