|
Atomistry » Fluorine » PDB 5lck-5lz4 » 5lp1 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5lck-5lz4 » 5lp1 » |
Fluorine in PDB 5lp1: Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.Enzymatic activity of Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.
All present enzymatic activity of Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.:
3.1.1.47; Protein crystallography data
The structure of Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution., PDB code: 5lp1
was solved by
D.Somers,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5lp1:
The structure of Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution. also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.
(pdb code 5lp1). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution., PDB code: 5lp1: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 5lp1Go back to Fluorine Binding Sites List in 5lp1
Fluorine binding site 1 out
of 4 in the Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 5lp1Go back to Fluorine Binding Sites List in 5lp1
Fluorine binding site 2 out
of 4 in the Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 5lp1Go back to Fluorine Binding Sites List in 5lp1
Fluorine binding site 3 out
of 4 in the Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 5lp1Go back to Fluorine Binding Sites List in 5lp1
Fluorine binding site 4 out
of 4 in the Crystal Structure of Human Lipoprotein-Associated Phospholipase A2 in Complex with A [1.1.1]Bicyclopentane-Containing Inhibitor at 1.91A Resolution.
Mono view Stereo pair view
Reference:
N.D.Measom,
K.D.Down,
D.J.Hirst,
C.Jamieson,
E.S.Manas,
V.K.Patel,
D.O.Somers.
Investigation of A Bicyclo[1.1.1]Pentane As A Phenyl Replacement Within An LPPLA2 Inhibitor. Acs Med Chem Lett V. 8 43 2017.
Page generated: Thu Aug 1 11:26:29 2024
ISSN: ISSN 1948-5875 PubMed: 28105273 DOI: 10.1021/ACSMEDCHEMLETT.6B00281 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |