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Atomistry » Fluorine » PDB 5lz5-5msa » 5mma | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5lz5-5msa » 5mma » |
Fluorine in PDB 5mma: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G)Enzymatic activity of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G)
All present enzymatic activity of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G):
2.7.7.49; 2.7.7.7; 3.1.26.4; Protein crystallography data
The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G), PDB code: 5mma
was solved by
D.P.Maskell,
V.E.Pye,
P.Cherepanov,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5mma:
The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G)
(pdb code 5mma). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G), PDB code: 5mma: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5mmaGo back to Fluorine Binding Sites List in 5mma
Fluorine binding site 1 out
of 2 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G)
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5mmaGo back to Fluorine Binding Sites List in 5mma
Fluorine binding site 2 out
of 2 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ379 (Compound 5'G)
Mono view Stereo pair view
Reference:
X.Z.Zhao,
S.J.Smith,
D.P.Maskell,
M.Metifiot,
V.E.Pye,
K.Fesen,
C.Marchand,
Y.Pommier,
P.Cherepanov,
S.H.Hughes,
T.R.Burke.
Structure-Guided Optimization of Hiv Integrase Strand Transfer Inhibitors. J. Med. Chem. V. 60 7315 2017.
Page generated: Sun Dec 13 12:28:04 2020
ISSN: ISSN 1520-4804 PubMed: 28737946 DOI: 10.1021/ACS.JMEDCHEM.7B00596 |
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