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Atomistry » Fluorine » PDB 5msb-5njh » 5mvc | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5msb-5njh » 5mvc » |
Fluorine in PDB 5mvc: Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole ScaffoldsEnzymatic activity of Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds
All present enzymatic activity of Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds:
1.3.5.2; Protein crystallography data
The structure of Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds, PDB code: 5mvc
was solved by
P.Goyal,
M.Andersson,
A.C.Moritzer,
S.Sainas,
A.C.Pippione,
D.Boschi,
S.Al-Kadaraghi,
M.Lolli,
R.Friemann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5mvc:
The structure of Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds
(pdb code 5mvc). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds, PDB code: 5mvc: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 5mvcGo back to Fluorine Binding Sites List in 5mvc
Fluorine binding site 1 out
of 4 in the Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 5mvcGo back to Fluorine Binding Sites List in 5mvc
Fluorine binding site 2 out
of 4 in the Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 5mvcGo back to Fluorine Binding Sites List in 5mvc
Fluorine binding site 3 out
of 4 in the Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 5mvcGo back to Fluorine Binding Sites List in 5mvc
Fluorine binding site 4 out
of 4 in the Crystal Structure of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds
Mono view Stereo pair view
Reference:
S.Sainas,
A.C.Pippione,
M.Giorgis,
E.Lupino,
P.Goyal,
C.Ramondetti,
B.Buccinna,
M.Piccinini,
R.C.Braga,
C.H.Andrade,
M.Andersson,
A.C.Moritzer,
R.Friemann,
S.Mensa,
S.Al-Kadaraghi,
D.Boschi,
M.L.Lolli.
Design, Synthesis, Biological Evaluation and X-Ray Structural Studies of Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on Hydroxylated Azole Scaffolds. Eur J Med Chem V. 129 287 2017.
Page generated: Sun Dec 13 12:28:22 2020
ISSN: ISSN 1768-3254 PubMed: 28235702 DOI: 10.1016/J.EJMECH.2017.02.017 |
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