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Atomistry » Fluorine » PDB 5msb-5njh » 5my8 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5msb-5njh » 5my8 » |
Fluorine in PDB 5my8: Crystal Structure of SRPK1 in Complex with SPHINX31Enzymatic activity of Crystal Structure of SRPK1 in Complex with SPHINX31
All present enzymatic activity of Crystal Structure of SRPK1 in Complex with SPHINX31:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of SRPK1 in Complex with SPHINX31, PDB code: 5my8
was solved by
A.Chaikuad,
F.Von Delft,
C.Bountra,
C.H.Arrowsmith,
A.M.Edwards,
S.Knapp,
Structural Genomics Consortium (Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of SRPK1 in Complex with SPHINX31
(pdb code 5my8). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of SRPK1 in Complex with SPHINX31, PDB code: 5my8: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5my8Go back to Fluorine Binding Sites List in 5my8
Fluorine binding site 1 out
of 3 in the Crystal Structure of SRPK1 in Complex with SPHINX31
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 5my8Go back to Fluorine Binding Sites List in 5my8
Fluorine binding site 2 out
of 3 in the Crystal Structure of SRPK1 in Complex with SPHINX31
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 5my8Go back to Fluorine Binding Sites List in 5my8
Fluorine binding site 3 out
of 3 in the Crystal Structure of SRPK1 in Complex with SPHINX31
Mono view Stereo pair view
Reference:
J.Batson,
H.D.Toop,
C.Redondo,
R.Babaei-Jadidi,
A.Chaikuad,
S.F.Wearmouth,
B.Gibbons,
C.Allen,
C.Tallant,
J.Zhang,
C.Du,
J.C.Hancox,
T.Hawtrey,
J.Da Rocha,
R.Griffith,
S.Knapp,
D.O.Bates,
J.C.Morris.
Development of Potent, Selective SRPK1 Inhibitors As Potential Topical Therapeutics For Neovascular Eye Disease. Acs Chem. Biol. V. 12 825 2017.
Page generated: Sun Dec 13 12:28:25 2020
ISSN: ESSN 1554-8937 PubMed: 28135068 DOI: 10.1021/ACSCHEMBIO.6B01048 |
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