Fluorine in PDB 5nd4: Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx

The structure of Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx also contains other interesting chemical elements:

Magnesium	(Mg)	2 atoms
Aluminium	(Al)	1 atom

The binding sites of Fluorine atom in the Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx (pdb code 5nd4). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx, PDB code: 5nd4:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in the Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx within 5.0Å range: probe atom residue distance (Å) B Occ C:F603 b:2.6 occ:1.00 F1 C:ALF603 0.0 2.6 1.0 AL C:ALF603 1.8 2.6 1.0 F3 C:ALF603 2.4 2.6 1.0 F4 C:ALF603 2.6 2.6 1.0 O3B C:ADP601 2.8 26.8 1.0 CA C:ALA409 3.0 0.5 1.0 O2B C:ADP601 3.1 26.8 1.0 NZ C:LYS165 3.2 0.7 1.0 N C:GLY410 3.2 0.4 1.0 MG C:MG602 3.3 0.4 1.0 CB C:ALA409 3.4 0.5 1.0 OG C:SER377 3.5 3.6 1.0 PB C:ADP601 3.5 26.8 1.0 F2 C:ALF603 3.5 2.6 1.0 C C:ALA409 3.6 0.5 1.0 O C:LEU408 3.9 9.6 1.0 CD C:LYS165 4.0 0.7 1.0 CE C:LYS165 4.1 0.7 1.0 O C:SER377 4.1 3.6 1.0 N C:ALA409 4.1 0.5 1.0 CB C:SER377 4.2 3.6 1.0 N C:SER377 4.3 3.6 1.0 O1B C:ADP601 4.4 26.8 1.0 C C:LEU408 4.4 9.6 1.0 CA C:GLY410 4.5 0.4 1.0 CA C:SER377 4.7 3.6 1.0 O3A C:ADP601 4.8 26.8 1.0 O C:ALA409 4.8 0.5 1.0 C C:SER377 4.9 3.6 1.0 OG1 C:THR166 5.0 17.7 1.0

Fluorine binding site 2 out of 4 in the Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx within 5.0Å range: probe atom residue distance (Å) B Occ C:F603 b:2.6 occ:1.00 F2 C:ALF603 0.0 2.6 1.0 AL C:ALF603 1.8 2.6 1.0 F3 C:ALF603 2.5 2.6 1.0 F4 C:ALF603 2.6 2.6 1.0 O3B C:ADP601 2.7 26.8 1.0 OG C:SER376 2.8 27.0 1.0 CB C:SER376 3.2 27.0 1.0 CA C:SER376 3.3 27.0 1.0 F1 C:ALF603 3.5 2.6 1.0 OD1 C:ASN373 3.6 2.1 1.0 CG2 C:THR161 3.9 0.3 1.0 ND2 C:ASN373 4.0 2.1 1.0 PB C:ADP601 4.0 26.8 1.0 OG1 C:THR161 4.0 0.3 1.0 N C:SER377 4.1 3.6 1.0 CG C:ASN373 4.2 2.1 1.0 C C:SER376 4.2 27.0 1.0 N C:SER376 4.3 27.0 1.0 O3A C:ADP601 4.3 26.8 1.0 CB C:THR161 4.4 0.3 1.0 CA C:THR161 4.5 0.3 1.0 N C:ASN162 4.5 0.1 1.0 O2B C:ADP601 4.7 26.8 1.0 MG C:MG602 4.7 0.4 1.0

Fluorine binding site 3 out of 4 in the Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx within 5.0Å range: probe atom residue distance (Å) B Occ C:F603 b:2.6 occ:1.00 F3 C:ALF603 0.0 2.6 1.0 AL C:ALF603 1.8 2.6 1.0 F1 C:ALF603 2.4 2.6 1.0 F2 C:ALF603 2.5 2.6 1.0 O3B C:ADP601 2.8 26.8 1.0 N C:GLY410 2.9 0.4 1.0 OG1 C:THR161 3.3 0.3 1.0 O C:GLY410 3.4 0.4 1.0 CA C:GLY410 3.6 0.4 1.0 F4 C:ALF603 3.6 2.6 1.0 C C:GLY410 3.8 0.4 1.0 C C:ALA409 3.8 0.5 1.0 CA C:ALA409 4.0 0.5 1.0 CB C:ALA409 4.1 0.5 1.0 CA C:THR161 4.1 0.3 1.0 CB C:THR161 4.2 0.3 1.0 PB C:ADP601 4.3 26.8 1.0 CG2 C:THR161 4.6 0.3 1.0 O C:SER377 4.7 3.6 1.0 O2B C:ADP601 4.8 26.8 1.0 N C:THR161 4.8 0.3 1.0 O C:ALA409 4.9 0.5 1.0 O1B C:ADP601 5.0 26.8 1.0 N C:SER411 5.0 0.2 1.0

Fluorine binding site 4 out of 4 in the Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Microtubule-Bound MKLP2 Motor Domain in the Presence of Adp.Alfx within 5.0Å range: probe atom residue distance (Å) B Occ C:F603 b:2.6 occ:1.00 F4 C:ALF603 0.0 2.6 1.0 AL C:ALF603 1.8 2.6 1.0 MG C:MG602 2.2 0.4 1.0 F2 C:ALF603 2.6 2.6 1.0 F1 C:ALF603 2.6 2.6 1.0 OG C:SER377 2.7 3.6 1.0 N C:SER377 2.8 3.6 1.0 O3B C:ADP601 2.8 26.8 1.0 O2B C:ADP601 3.0 26.8 1.0 CA C:SER376 3.1 27.0 1.0 PB C:ADP601 3.2 26.8 1.0 C C:SER376 3.4 27.0 1.0 F3 C:ALF603 3.6 2.6 1.0 O3A C:ADP601 3.6 26.8 1.0 OG1 C:THR166 3.7 17.7 1.0 CB C:SER377 3.8 3.6 1.0 CA C:SER377 3.8 3.6 1.0 N C:SER376 3.9 27.0 1.0 CB C:SER376 4.1 27.0 1.0 O1A C:ADP601 4.1 26.8 1.0 OG C:SER376 4.3 27.0 1.0 O C:SER377 4.4 3.6 1.0 ND2 C:ASN373 4.4 2.1 1.0 NZ C:LYS165 4.5 0.7 1.0 PA C:ADP601 4.5 26.8 1.0 O C:GLN375 4.5 73.2 1.0 C C:GLN375 4.5 73.2 1.0 C C:SER377 4.6 3.6 1.0 O1B C:ADP601 4.6 26.8 1.0 O C:SER376 4.6 27.0 1.0

J.Atherton, I.M.Yu, A.Cook, J.M.Muretta, A.Joseph, J.Major, Y.Sourigues, J.Clause, M.Topf, S.S.Rosenfeld, A.Houdusse, C.A.Moores. The Divergent Mitotic Kinesin MKLP2 Exhibits Atypical Structure and Mechanochemistry. Elife V. 6 2017.
ISSN: ESSN 2050-084X
PubMed: 28826477
DOI: 10.7554/ELIFE.27793