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Atomistry » Fluorine » PDB 5nk2-5o6h » 5no1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5nk2-5o6h » 5no1 » |
Fluorine in PDB 5no1: Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)Enzymatic activity of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
All present enzymatic activity of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G):
2.7.7.49; 2.7.7.7; 3.1.26.4; Protein crystallography data
The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G), PDB code: 5no1
was solved by
V.E.Pye,
P.Cherepanov,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5no1:
The structure of Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
(pdb code 5no1). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G), PDB code: 5no1: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 5no1Go back to Fluorine Binding Sites List in 5no1
Fluorine binding site 1 out
of 2 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 5no1Go back to Fluorine Binding Sites List in 5no1
Fluorine binding site 2 out
of 2 in the Crystal Structure of the Prototype Foamy Virus (Pfv) Intasome in Complex with Magnesium and the Insti XZ407 (Compound 5G)
Mono view Stereo pair view
Reference:
X.Z.Zhao,
S.J.Smith,
D.P.Maskell,
M.Metifiot,
V.E.Pye,
K.Fesen,
C.Marchand,
Y.Pommier,
P.Cherepanov,
S.H.Hughes,
T.R.Burke.
Structure-Guided Optimization of Hiv Integrase Strand Transfer Inhibitors. J. Med. Chem. V. 60 7315 2017.
Page generated: Thu Aug 1 12:03:45 2024
ISSN: ISSN 1520-4804 PubMed: 28737946 DOI: 10.1021/ACS.JMEDCHEM.7B00596 |
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