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Atomistry » Fluorine » PDB 5olw-5p92 » 5os8 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5olw-5p92 » 5os8 » |
Fluorine in PDB 5os8: The Crystal Structure of CK2ALPHA in Complex with Compound 11Enzymatic activity of The Crystal Structure of CK2ALPHA in Complex with Compound 11
All present enzymatic activity of The Crystal Structure of CK2ALPHA in Complex with Compound 11:
2.7.11.1; Protein crystallography data
The structure of The Crystal Structure of CK2ALPHA in Complex with Compound 11, PDB code: 5os8
was solved by
P.Brear,
C.De Fusco,
J.Iegre,
M.Yoshida,
S.Mitchell,
M.Rossmann,
L.Carro,
H.Sore,
M.Hyvonen,
D.Spring,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5os8:
The structure of The Crystal Structure of CK2ALPHA in Complex with Compound 11 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The Crystal Structure of CK2ALPHA in Complex with Compound 11
(pdb code 5os8). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the The Crystal Structure of CK2ALPHA in Complex with Compound 11, PDB code: 5os8: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 5os8Go back to Fluorine Binding Sites List in 5os8
Fluorine binding site 1 out
of 4 in the The Crystal Structure of CK2ALPHA in Complex with Compound 11
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 5os8Go back to Fluorine Binding Sites List in 5os8
Fluorine binding site 2 out
of 4 in the The Crystal Structure of CK2ALPHA in Complex with Compound 11
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 5os8Go back to Fluorine Binding Sites List in 5os8
Fluorine binding site 3 out
of 4 in the The Crystal Structure of CK2ALPHA in Complex with Compound 11
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 5os8Go back to Fluorine Binding Sites List in 5os8
Fluorine binding site 4 out
of 4 in the The Crystal Structure of CK2ALPHA in Complex with Compound 11
Mono view Stereo pair view
Reference:
J.Iegre,
P.Brear,
C.De Fusco,
M.Yoshida,
S.L.Mitchell,
M.Rossmann,
L.Carro,
H.F.Sore,
M.Hyvonen,
D.R.Spring.
Second-Generation CK2 Alpha Inhibitors Targeting the Alpha D Pocket. Chem Sci V. 9 3041 2018.
Page generated: Sun Dec 13 12:30:13 2020
ISSN: ISSN 2041-6520 PubMed: 29732088 DOI: 10.1039/C7SC05122K |
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