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Fluorine in PDB 5t8j: Synthesis and Biological Evaluation of Novel Selective Androgen Receptor Modulators (Sarms). Part II: Optimization of 4-(Pyrrolidin- 1-Yl)Benzonitrile DerivativesProtein crystallography data
The structure of Synthesis and Biological Evaluation of Novel Selective Androgen Receptor Modulators (Sarms). Part II: Optimization of 4-(Pyrrolidin- 1-Yl)Benzonitrile Derivatives, PDB code: 5t8j
was solved by
K.P.Wilson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Synthesis and Biological Evaluation of Novel Selective Androgen Receptor Modulators (Sarms). Part II: Optimization of 4-(Pyrrolidin- 1-Yl)Benzonitrile Derivatives
(pdb code 5t8j). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Synthesis and Biological Evaluation of Novel Selective Androgen Receptor Modulators (Sarms). Part II: Optimization of 4-(Pyrrolidin- 1-Yl)Benzonitrile Derivatives, PDB code: 5t8j: Fluorine binding site 1 out of 1 in 5t8jGo back to Fluorine Binding Sites List in 5t8j
Fluorine binding site 1 out
of 1 in the Synthesis and Biological Evaluation of Novel Selective Androgen Receptor Modulators (Sarms). Part II: Optimization of 4-(Pyrrolidin- 1-Yl)Benzonitrile Derivatives
Mono view Stereo pair view
Reference:
M.Asano,
T.Hitaka,
T.Imada,
M.Yamada,
M.Morimoto,
H.Shinohara,
T.Hara,
M.Yamaoka,
T.Santou,
M.Nakayama,
Y.Imai,
N.Habuka,
J.Yano,
K.Wilson,
H.Fujita,
A.Hasuoka.
Synthesis and Biological Evaluation of Novel Selective Androgen Receptor Modulators (Sarms). Part II: Optimization of 4-(Pyrrolidin-1-Yl)Benzonitrile Derivatives. Bioorg. Med. Chem. Lett. V. 27 1897 2017.
Page generated: Sun Dec 13 12:37:47 2020
ISSN: ESSN 1464-3405 PubMed: 28363748 DOI: 10.1016/J.BMCL.2017.03.038 |
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