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Atomistry » Fluorine » PDB 5tbm-5tto » 5tn7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5tbm-5tto » 5tn7 » |
Fluorine in PDB 5tn7: Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-OlateProtein crystallography data
The structure of Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate, PDB code: 5tn7
was solved by
J.C.Nwachukwu,
S.Srinivasan,
N.E.Bruno,
J.Nowak,
D.J.Kojetin,
F.Minutolo,
O.Elemento,
J.A.Katzenellenbogen,
K.W.Nettles,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate
(pdb code 5tn7). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate, PDB code: 5tn7: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 5tn7Go back to Fluorine Binding Sites List in 5tn7
Fluorine binding site 1 out
of 3 in the Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 5tn7Go back to Fluorine Binding Sites List in 5tn7
Fluorine binding site 2 out
of 3 in the Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 5tn7Go back to Fluorine Binding Sites List in 5tn7
Fluorine binding site 3 out
of 3 in the Crystal Structure of the Er-Alpha Ligand-Binding Domain (Y537S) in Complex with (E)-3'-Fluoro-4'-Hydroxy-3-((Hydroxyiminio)Methyl)-[1, 1'-Biphenyl]-4-Olate
Mono view Stereo pair view
Reference:
J.C.Nwachukwu,
S.Srinivasan,
N.E.Bruno,
J.Nowak,
N.J.Wright,
F.Minutolo,
E.S.Rangarajan,
T.Izard,
X.Q.Yao,
B.J.Grant,
D.J.Kojetin,
O.Elemento,
J.A.Katzenellenbogen,
K.W.Nettles.
Systems Structural Biology Analysis of Ligand Effects on Er Alpha Predicts Cellular Response to Environmental Estrogens and Anti-Hormone Therapies. Cell Chem Biol V. 24 35 2017.
Page generated: Thu Aug 1 15:16:29 2024
ISSN: ESSN 2451-9456 PubMed: 28042045 DOI: 10.1016/J.CHEMBIOL.2016.11.014 |
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