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Atomistry » Fluorine » PDB 5tbo-5tvj » 5tq8 » |
Fluorine in PDB 5tq8: Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and SkinEnzymatic activity of Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin
All present enzymatic activity of Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin:
2.7.10.2; Protein crystallography data
The structure of Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin, PDB code: 5tq8
was solved by
J.Chrencik,
P.Jones,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin
(pdb code 5tq8). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin, PDB code: 5tq8: Fluorine binding site 1 out of 1 in 5tq8Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Design and Synthesis of A Pan-Jak Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin
![]() Mono view ![]() Stereo pair view
Reference:
P.Jones,
R.I.Storer,
Y.A.Sabnis,
F.M.Wakenhut,
G.A.Whitlock,
K.S.England,
T.Mukaiyama,
C.M.Dehnhardt,
J.W.Coe,
S.W.Kortum,
J.E.Chrencik,
D.G.Brown,
R.M.Jones,
J.R.Murphy,
T.Yeoh,
P.Morgan,
I.Kilty.
Design and Synthesis of A Pan-Janus Kinase Inhibitor Clinical Candidate (Pf-06263276) Suitable For Inhaled and Topical Delivery For the Treatment of Inflammatory Diseases of the Lungs and Skin. J. Med. Chem. V. 60 767 2017.
Page generated: Tue Jul 15 08:01:03 2025
ISSN: ISSN 1520-4804 PubMed: 27983835 DOI: 10.1021/ACS.JMEDCHEM.6B01634 |
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