|
Fluorine in PDB 5ukk: Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK)Enzymatic activity of Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK)
All present enzymatic activity of Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK):
2.7.11.15; Protein crystallography data
The structure of Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK), PDB code: 5ukk
was solved by
M.C.Cato,
K.T.Homan,
J.J.G.Tesmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5ukk:
The structure of Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK)
(pdb code 5ukk). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK), PDB code: 5ukk: Fluorine binding site 1 out of 1 in 5ukkGo back to Fluorine Binding Sites List in 5ukk
Fluorine binding site 1 out
of 1 in the Human GRK2 in Complex with Human G-Beta-Gamma Subunits and CCG211998 (14AK)
Mono view Stereo pair view
Reference:
H.V.Waldschmidt,
K.T.Homan,
M.C.Cato,
O.Cruz-Rodriguez,
A.Cannavo,
M.W.Wilson,
J.Song,
J.Y.Cheung,
W.J.Koch,
J.J.Tesmer,
S.D.Larsen.
Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J. Med. Chem. V. 60 3052 2017.
Page generated: Sun Dec 13 12:39:21 2020
ISSN: ISSN 1520-4804 PubMed: 28323425 DOI: 10.1021/ACS.JMEDCHEM.7B00112 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |