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Fluorine in PDB 5uoq: Crystal Structure of the Prototype Foamy Virus Intasome with A 2- Pyridinone Aminal Inhibitor (Compound 31)Protein crystallography data
The structure of Crystal Structure of the Prototype Foamy Virus Intasome with A 2- Pyridinone Aminal Inhibitor (Compound 31), PDB code: 5uoq
was solved by
D.J.Klein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5uoq:
The structure of Crystal Structure of the Prototype Foamy Virus Intasome with A 2- Pyridinone Aminal Inhibitor (Compound 31) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Prototype Foamy Virus Intasome with A 2- Pyridinone Aminal Inhibitor (Compound 31)
(pdb code 5uoq). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Prototype Foamy Virus Intasome with A 2- Pyridinone Aminal Inhibitor (Compound 31), PDB code: 5uoq: Fluorine binding site 1 out of 1 in 5uoqGo back to Fluorine Binding Sites List in 5uoq
Fluorine binding site 1 out
of 1 in the Crystal Structure of the Prototype Foamy Virus Intasome with A 2- Pyridinone Aminal Inhibitor (Compound 31)
Mono view Stereo pair view
Reference:
J.D.Schreier,
M.W.Embrey,
I.T.Raheem,
G.Barbe,
L.C.Campeau,
D.Dubost,
J.Mccabe Dunn,
J.Grobler,
T.J.Hartingh,
D.J.Hazuda,
D.Klein,
M.D.Miller,
K.P.Moore,
N.Nguyen,
N.Pajkovic,
D.A.Powell,
V.Rada,
J.M.Sanders,
J.Sisko,
T.G.Steele,
J.Wai,
A.Walji,
M.Xu,
P.J.Coleman.
Discovery and Optimization of 2-Pyridinone Aminal Integrase Strand Transfer Inhibitors For the Treatment of Hiv. Bioorg. Med. Chem. Lett. V. 27 2038 2017.
Page generated: Sun Dec 13 12:39:32 2020
ISSN: ESSN 1464-3405 PubMed: 28285916 DOI: 10.1016/J.BMCL.2017.02.039 |
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