Atomistry » Fluorine » PDB 5ug8-5uv1 » 5uqa
Atomistry »
  Fluorine »
    PDB 5ug8-5uv1 »
      5uqa »

Fluorine in PDB 5uqa: Insulin with Proline Analog Fzp at Position B28 in the R6 State

Protein crystallography data

The structure of Insulin with Proline Analog Fzp at Position B28 in the R6 State, PDB code: 5uqa was solved by S.A.Lieblich, K.Y.Fang, D.A.Tirrell, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.53 / 1.31
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 46.936, 61.258, 60.390, 90.00, 111.69, 90.00
R / Rfree (%) 15.2 / 18.2

Other elements in 5uqa:

The structure of Insulin with Proline Analog Fzp at Position B28 in the R6 State also contains other interesting chemical elements:

Zinc (Zn) 2 atoms
Chlorine (Cl) 2 atoms
Sodium (Na) 6 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Insulin with Proline Analog Fzp at Position B28 in the R6 State (pdb code 5uqa). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Insulin with Proline Analog Fzp at Position B28 in the R6 State, PDB code: 5uqa:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;

Fluorine binding site 1 out of 6 in 5uqa

Go back to Fluorine Binding Sites List in 5uqa
Fluorine binding site 1 out of 6 in the Insulin with Proline Analog Fzp at Position B28 in the R6 State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Insulin with Proline Analog Fzp at Position B28 in the R6 State within 5.0Å range:
probe atom residue distance (Å) B Occ
B:F28

b:28.0
occ:1.00
FGX B:4FB28 0.0 28.0 1.0
CGX B:4FB28 1.4 26.6 1.0
CBX B:4FB28 2.3 26.9 1.0
CDX B:4FB28 2.4 28.0 1.0
CA D:GLU21 2.9 21.6 1.0
CA B:4FB28 3.0 26.2 1.0
O D:GLY20 3.0 20.1 1.0
N B:4FB28 3.0 26.4 1.0
C B:4FB28 3.1 29.1 1.0
N D:GLU21 3.1 20.1 1.0
C D:GLY20 3.1 18.3 1.0
N B:LYS29 3.2 30.9 1.0
CG D:GLU21 3.3 26.7 1.0
CB D:GLU21 3.7 24.1 1.0
O B:4FB28 3.8 29.6 1.0
C D:GLU21 4.0 21.6 1.0
CA B:LYS29 4.2 34.2 1.0
CA D:GLY20 4.2 18.2 1.0
O B:HOH411 4.2 27.7 1.0
OG1 B:THR27 4.2 29.6 1.0
C B:THR27 4.3 27.9 1.0
O D:HOH216 4.3 22.1 1.0
O D:GLU21 4.4 25.5 1.0
CD D:GLU21 4.7 33.2 1.0
CB B:LYS29 4.8 34.6 1.0
N D:ARG22 4.9 20.6 1.0
O D:HOH213 4.9 21.4 1.0
CA B:THR27 5.0 26.4 1.0

Fluorine binding site 2 out of 6 in 5uqa

Go back to Fluorine Binding Sites List in 5uqa
Fluorine binding site 2 out of 6 in the Insulin with Proline Analog Fzp at Position B28 in the R6 State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Insulin with Proline Analog Fzp at Position B28 in the R6 State within 5.0Å range:
probe atom residue distance (Å) B Occ
D:F28

b:36.1
occ:1.00
FGX D:4FB28 0.0 36.1 1.0
CGX D:4FB28 1.4 34.8 1.0
CBX D:4FB28 2.3 33.9 1.0
CDX D:4FB28 2.4 35.1 1.0
O B:GLY20 3.0 31.8 1.0
CA B:GLU21 3.0 32.7 1.0
CA D:4FB28 3.1 33.7 1.0
N D:4FB28 3.1 34.7 1.0
O D:4FB28 3.2 35.7 1.0
C B:GLY20 3.2 32.2 1.0
C D:4FB28 3.3 34.4 1.0
N B:GLU21 3.3 32.4 1.0
CG B:GLU21 3.5 33.2 1.0
CB B:GLU21 3.8 33.7 1.0
C B:GLU21 4.1 34.5 1.0
CA B:GLY20 4.3 29.5 1.0
C D:THR27 4.3 33.0 1.0
O D:HOH204 4.4 35.7 1.0
O B:GLU21 4.4 37.5 1.0
OG1 D:THR27 4.5 40.0 1.0
O B:HOH412 4.7 40.8 1.0
O B:HOH408 4.9 28.9 1.0
N B:ARG22 5.0 33.3 1.0
CA D:THR27 5.0 32.4 1.0

Fluorine binding site 3 out of 6 in 5uqa

Go back to Fluorine Binding Sites List in 5uqa
Fluorine binding site 3 out of 6 in the Insulin with Proline Analog Fzp at Position B28 in the R6 State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Insulin with Proline Analog Fzp at Position B28 in the R6 State within 5.0Å range:
probe atom residue distance (Å) B Occ
F:F28

b:37.9
occ:1.00
FGX F:4FB28 0.0 37.9 1.0
CGX F:4FB28 1.4 35.3 1.0
CBX F:4FB28 2.3 33.8 1.0
CDX F:4FB28 2.4 31.8 1.0
O H:GLU21 3.1 29.2 1.0
N F:4FB28 3.1 29.4 1.0
CA F:4FB28 3.1 32.5 1.0
CA H:GLU21 3.2 27.9 1.0
C F:4FB28 3.4 35.6 1.0
C H:GLU21 3.5 27.0 1.0
N F:LYS29 3.6 37.8 1.0
CB H:GLU21 3.8 31.9 1.0
O F:4FB28 4.1 37.3 1.0
O F:HOH215 4.2 40.3 1.0
O H:GLY20 4.2 22.5 1.0
CG H:GLU21 4.3 36.8 1.0
N H:GLU21 4.3 26.8 1.0
C F:THR27 4.4 25.6 1.0
CA F:LYS29 4.5 41.1 1.0
C H:GLY20 4.7 24.6 1.0
N H:ARG22 4.7 23.8 0.4
N H:ARG22 4.7 24.7 0.6
OG1 F:THR27 4.8 29.6 0.7
CG2 F:THR27 4.9 30.5 0.3
CA F:THR27 5.0 25.8 0.3
CA F:THR27 5.0 24.8 0.7

Fluorine binding site 4 out of 6 in 5uqa

Go back to Fluorine Binding Sites List in 5uqa
Fluorine binding site 4 out of 6 in the Insulin with Proline Analog Fzp at Position B28 in the R6 State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Insulin with Proline Analog Fzp at Position B28 in the R6 State within 5.0Å range:
probe atom residue distance (Å) B Occ
H:F28

b:39.9
occ:1.00
FGX H:4FB28 0.0 39.9 1.0
CGX H:4FB28 1.4 36.0 1.0
CBX H:4FB28 2.3 36.5 1.0
CDX H:4FB28 2.4 34.1 1.0
O F:HOH214 3.0 48.6 1.0
N H:4FB28 3.0 34.3 1.0
CA H:4FB28 3.1 35.1 1.0
O F:GLU21 3.3 30.7 1.0
C H:4FB28 3.5 37.5 1.0
CA F:GLU21 3.7 29.4 1.0
O F:HOH217 3.7 39.5 1.0
C F:GLU21 3.7 27.6 1.0
O F:GLY20 4.1 25.1 1.0
C H:THR27 4.2 34.6 1.0
O H:4FB28 4.3 37.5 1.0
N F:GLY23 4.5 22.4 1.0
CB F:GLU21 4.5 29.4 1.0
N F:GLU21 4.7 29.8 1.0
CA F:GLY23 4.7 22.0 1.0
C F:GLY20 4.8 25.9 1.0
CA H:THR27 4.8 31.5 1.0
N F:ARG22 4.8 26.0 1.0
CE2 H:TYR26 4.9 25.5 1.0

Fluorine binding site 5 out of 6 in 5uqa

Go back to Fluorine Binding Sites List in 5uqa
Fluorine binding site 5 out of 6 in the Insulin with Proline Analog Fzp at Position B28 in the R6 State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Insulin with Proline Analog Fzp at Position B28 in the R6 State within 5.0Å range:
probe atom residue distance (Å) B Occ
J:F28

b:35.2
occ:1.00
FGX J:4FB28 0.0 35.2 1.0
CGX J:4FB28 1.4 33.0 1.0
CBX J:4FB28 2.3 32.3 1.0
CDX J:4FB28 2.4 30.8 1.0
N J:4FB28 3.0 28.3 1.0
CA J:4FB28 3.1 30.7 1.0
O J:4FB28 3.3 36.2 1.0
O L:HOH212 3.4 51.9 1.0
C J:4FB28 3.4 33.8 1.0
O L:GLU21 3.5 35.3 1.0
CA L:GLU21 3.6 31.5 1.0
C L:GLU21 3.9 33.3 1.0
C J:THR27 4.2 29.0 1.0
CB L:GLU21 4.3 31.9 1.0
O L:GLY20 4.4 30.1 1.0
CG2 J:THR27 4.6 33.9 1.0
N L:GLU21 4.7 31.3 1.0
CA J:THR27 4.7 29.7 1.0
C L:GLY20 4.9 30.6 1.0

Fluorine binding site 6 out of 6 in 5uqa

Go back to Fluorine Binding Sites List in 5uqa
Fluorine binding site 6 out of 6 in the Insulin with Proline Analog Fzp at Position B28 in the R6 State


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Insulin with Proline Analog Fzp at Position B28 in the R6 State within 5.0Å range:
probe atom residue distance (Å) B Occ
L:F28

b:48.9
occ:1.00
FGX L:4FB28 0.0 48.9 1.0
CGX L:4FB28 1.4 46.4 1.0
CBX L:4FB28 2.3 45.8 1.0
CDX L:4FB28 2.4 44.5 1.0
O J:GLU21 2.6 35.4 1.0
CA J:GLU21 3.0 30.7 1.0
C J:GLU21 3.0 32.1 1.0
N L:4FB28 3.1 42.5 1.0
N L:LYS29 3.1 49.4 1.0
CA L:4FB28 3.1 44.5 1.0
C L:4FB28 3.5 47.1 1.0
O J:GLY20 3.5 24.6 1.0
CB J:GLU21 3.9 32.5 1.0
N J:GLU21 4.0 28.0 1.0
CB L:LYS29 4.1 53.1 1.0
N J:ARG22 4.1 30.6 1.0
N J:GLY23 4.1 26.1 1.0
C J:GLY20 4.1 25.6 1.0
CA L:LYS29 4.2 52.5 1.0
C L:THR27 4.2 40.8 1.0
C J:ARG22 4.5 29.9 1.0
O L:4FB28 4.6 48.1 1.0
CA J:GLY23 4.6 24.0 1.0
CA L:THR27 4.8 36.3 1.0
CA J:ARG22 4.8 30.5 1.0

Reference:

S.A.Lieblich, K.Y.Fang, D.A.Tirrell. Insulin with Proline Analog Fzp at Position B28 in the R6 State To Be Published.
Page generated: Thu Aug 1 15:42:36 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy