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Atomistry » Fluorine » PDB 5uv3-5vd4 » 5v4w | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5uv3-5vd4 » 5v4w » |
Fluorine in PDB 5v4w: Human Glucokinase in Complex with Novel Indazole Activator.Enzymatic activity of Human Glucokinase in Complex with Novel Indazole Activator.
All present enzymatic activity of Human Glucokinase in Complex with Novel Indazole Activator.:
2.7.1.2; Protein crystallography data
The structure of Human Glucokinase in Complex with Novel Indazole Activator., PDB code: 5v4w
was solved by
R.J.Skene,
D.J.Hosfield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5v4w:
The structure of Human Glucokinase in Complex with Novel Indazole Activator. also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Glucokinase in Complex with Novel Indazole Activator.
(pdb code 5v4w). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human Glucokinase in Complex with Novel Indazole Activator., PDB code: 5v4w: Fluorine binding site 1 out of 1 in 5v4wGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Human Glucokinase in Complex with Novel Indazole Activator.
![]() Mono view ![]() Stereo pair view
Reference:
Z.S.Cheruvallath,
S.L.Gwaltney,
M.Sabat,
M.Tang,
H.Wang,
A.Jennings,
D.Hosfield,
B.Lee,
Y.Wu,
P.Halkowycz,
C.E.Grimshaw.
Discovery of Potent and Orally Active 1,4-Disubstituted Indazoles As Novel Allosteric Glucokinase Activators. Bioorg. Med. Chem. Lett. V. 27 2678 2017.
Page generated: Tue Jul 15 08:27:04 2025
ISSN: ESSN 1464-3405 PubMed: 28512030 DOI: 10.1016/J.BMCL.2017.04.041 |
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