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Fluorine in PDB 5vd4: Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue
Enzymatic activity of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue
All present enzymatic activity of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue:
2.7.10.2;
2.7.10.2;
Protein crystallography data
The structure of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue, PDB code: 5vd4
was solved by
J.-Y.Zhu,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 63.19 / 2.02 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 50.310, 43.780, 64.860, 90.00, 103.04, 90.00 |
| R / Rfree (%) | 20.3 / 24.5 |
Other elements in 5vd4:
The structure of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue also contains other interesting chemical elements:
| Chlorine | (Cl) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue
(pdb code 5vd4). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue, PDB code: 5vd4:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue, PDB code: 5vd4:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 5vd4
Go back to
Fluorine Binding Sites List in 5vd4
Fluorine binding site 1 out
of 3 in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 5vd4
Go back to
Fluorine Binding Sites List in 5vd4
Fluorine binding site 2 out
of 3 in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 5vd4
Go back to
Fluorine Binding Sites List in 5vd4
Fluorine binding site 3 out
of 3 in the Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Human WEE1 Kinase Domain in Complex with Rac-IV- 016, A MK1775 Analougue within 5.0Å range:
|
Reference:
J.-Y.Zhu,
E.Schonbrunn.
Structural Basis of Wee Family Kinase Inhibition By Small Molecules To Be Published.
Page generated: Thu Aug 1 16:07:06 2024
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