Fluorine in PDB 5wcf: Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae)

Enzymatic activity of Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae)

All present enzymatic activity of Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae):
2.1.1.319;

Protein crystallography data

The structure of Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae), PDB code: 5wcf was solved by A.Dong, H.Zeng, A.Hutch, A.Seitova, J.R.Walker, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 1.98
Space group I 41
Cell size a, b, c (Å), α, β, γ (°) 94.721, 94.721, 108.713, 90.00, 90.00, 90.00
R / Rfree (%) 20 / 20.8

Other elements in 5wcf:

The structure of Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae) also contains other interesting chemical elements:

Bromine (Br) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae) (pdb code 5wcf). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae), PDB code: 5wcf:

Fluorine binding site 1 out of 1 in 5wcf

Go back to Fluorine Binding Sites List in 5wcf
Fluorine binding site 1 out of 1 in the Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae)


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human HMT1 Hnrnp Methyltransferase-Like Protein 6 (S. Cerevisiae) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F402

b:39.5
occ:0.70
 F A:A0S402 0.0 39.5 0.7
C16 A:A0S402 1.4 36.5 0.7
CD1 A:LEU161 1.8 27.9 0.3
CD2 A:LEU161 2.2 28.2 0.3
CG A:LEU161 2.3 27.8 0.3
C15 A:A0S402 2.3 34.0 0.7
C17 A:A0S402 2.4 37.3 0.7
CB A:ALA189 3.2 35.3 1.0
CB A:LEU161 3.3 28.1 0.3
CB A:PHE292 3.4 34.3 1.0
C14 A:A0S402 3.6 36.5 0.7
C18 A:A0S402 3.6 37.5 0.7
CG A:PHE292 3.7 34.2 1.0
CH2 A:TRP156 3.8 37.7 1.0
CD1 A:PHE292 4.0 36.3 1.0
C13 A:A0S402 4.1 35.9 0.7
CZ3 A:TRP156 4.2 36.4 1.0
CA A:LEU161 4.4 28.6 0.3
O A:GLN293 4.4 32.6 1.0
CA A:ALA189 4.5 34.3 1.0
CG A:MET157 4.5 32.2 0.7
CD2 A:PHE292 4.5 33.9 1.0
CD2 A:LEU191 4.6 39.1 1.0
O A:GLU190 4.6 33.9 1.0
CG1 A:VAL294 4.6 36.0 1.0
CG A:MET157 4.6 32.1 0.3
CG A:LEU191 4.7 34.0 1.0
N A:GLU190 4.7 32.8 1.0
CA A:PHE292 4.8 33.0 1.0
CZ2 A:TRP156 4.8 36.8 1.0
C A:ALA189 4.8 36.2 1.0
CE1 A:PHE292 4.9 36.1 1.0
CB A:MET157 5.0 32.9 0.7

Reference:

H.Zeng, A.Dong, A.Hutch, A.Seitova, J.R.Walker, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc). The Crystal Structure of Human HMT1 Hnrnp Methyltransferase-Like Protein 6 in Complex with MTLLE1441 To Be Published.
Page generated: Sun Dec 13 12:41:41 2020

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