Fluorine in PDB 5wek: GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1

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>>> Page 1 <<< Page 2, Binding sites: 11 - 12;

Binding sites:

The binding sites of Fluorine atom in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 (pdb code 5wek). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1, PDB code: 5wek:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Fluorine binding site 1 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:0.6 occ:1.00 FAF A:ZK11301 0.0 0.6 1.0 CAZ A:ZK11301 1.4 0.6 1.0 FAG A:ZK11301 2.2 0.6 1.0 FAH A:ZK11301 2.2 0.6 1.0 CAS A:ZK11301 2.4 0.6 1.0 OE1 A:GLU705 2.7 0.8 1.0 OH A:TYR732 3.1 0.1 1.0 CAR A:ZK11301 3.2 0.6 1.0 CAM A:ZK11301 3.3 0.6 1.0 CAJ A:ZK11301 3.3 0.6 1.0 NAX A:ZK11301 3.3 0.6 1.0 CD A:GLU705 3.8 0.8 1.0 CAK A:ZK11301 3.9 0.6 1.0 CZ A:TYR732 4.1 0.1 1.0 OE2 A:GLU705 4.3 0.8 1.0 CE2 A:TYR732 4.3 0.1 1.0 CAI A:ZK11301 4.4 0.6 1.0 CAN A:ZK11301 4.5 0.6 1.0 CAV A:ZK11301 4.5 0.6 1.0 CB A:MET708 4.8 0.0 1.0 OH A:TYR450 4.8 0.6 1.0 CG A:GLU705 4.9 0.8 1.0 CB A:GLU705 4.9 0.8 1.0 CAL A:ZK11301 5.0 0.6 1.0 CAW A:ZK11301 5.0 0.6 1.0

Fluorine binding site 2 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:0.6 occ:1.00 FAG A:ZK11301 0.0 0.6 1.0 CAZ A:ZK11301 1.4 0.6 1.0 FAH A:ZK11301 2.2 0.6 1.0 FAF A:ZK11301 2.2 0.6 1.0 CAS A:ZK11301 2.3 0.6 1.0 CAJ A:ZK11301 2.6 0.6 1.0 CB A:PRO478 3.4 0.8 1.0 OH A:TYR732 3.6 0.1 1.0 CAR A:ZK11301 3.7 0.6 1.0 OH A:TYR450 3.7 0.6 1.0 CE2 A:TYR732 3.9 0.1 1.0 CZ A:TYR732 4.0 0.1 1.0 CAV A:ZK11301 4.0 0.6 1.0 CG A:PRO478 4.1 0.8 1.0 O A:PRO478 4.2 0.8 1.0 CE1 A:TYR450 4.2 0.6 1.0 CZ A:TYR450 4.2 0.6 1.0 NAX A:ZK11301 4.3 0.6 1.0 OE1 A:GLU705 4.4 0.8 1.0 CE2 A:TYR405 4.7 0.8 1.0 CA A:PRO478 4.7 0.8 1.0 C A:PRO478 4.7 0.8 1.0 CG A:GLU402 4.7 0.8 1.0 CAI A:ZK11301 4.8 0.6 1.0 NAP A:ZK11301 4.8 0.6 1.0 CD2 A:TYR405 4.8 0.8 1.0 CAW A:ZK11301 4.9 0.6 1.0 CD2 A:TYR732 4.9 0.1 1.0 CAM A:ZK11301 4.9 0.6 1.0

Fluorine binding site 3 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1301 b:0.6 occ:1.00 FAH A:ZK11301 0.0 0.6 1.0 CAZ A:ZK11301 1.4 0.6 1.0 FAG A:ZK11301 2.2 0.6 1.0 FAF A:ZK11301 2.2 0.6 1.0 CAS A:ZK11301 2.4 0.6 1.0 NAX A:ZK11301 2.9 0.6 1.0 OH A:TYR450 2.9 0.6 1.0 CAR A:ZK11301 3.0 0.6 1.0 CAN A:ZK11301 3.3 0.6 1.0 OE1 A:GLU402 3.4 0.8 1.0 CAM A:ZK11301 3.5 0.6 1.0 CAJ A:ZK11301 3.6 0.6 1.0 CAL A:ZK11301 3.7 0.6 1.0 CD A:GLU402 3.7 0.8 1.0 CAK A:ZK11301 3.8 0.6 1.0 CZ A:TYR450 3.9 0.6 1.0 CG A:GLU402 4.0 0.8 1.0 CAI A:ZK11301 4.3 0.6 1.0 OAQ A:ZK11301 4.3 0.6 1.0 OE2 A:GLU402 4.4 0.8 1.0 CE1 A:TYR450 4.5 0.6 1.0 CB A:GLU402 4.6 0.8 1.0 OE1 A:GLU705 4.7 0.8 1.0 CAV A:ZK11301 4.7 0.6 1.0 CE2 A:TYR450 4.8 0.6 1.0 OH A:TYR732 4.9 0.1 1.0

Fluorine binding site 4 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1301 b:0.3 occ:1.00 FAF B:ZK11301 0.0 0.3 1.0 CAZ B:ZK11301 1.4 0.3 1.0 FAG B:ZK11301 2.2 0.3 1.0 FAH B:ZK11301 2.2 0.3 1.0 CAS B:ZK11301 2.4 0.3 1.0 OE1 B:GLU705 3.1 0.9 1.0 OH B:TYR732 3.2 0.6 1.0 CAR B:ZK11301 3.2 0.3 1.0 CAJ B:ZK11301 3.3 0.3 1.0 CAM B:ZK11301 3.4 0.3 1.0 NAX B:ZK11301 3.5 0.3 1.0 CAK B:ZK11301 4.0 0.3 1.0 CZ B:TYR732 4.1 0.6 1.0 CE2 B:TYR732 4.1 0.6 1.0 CD B:GLU705 4.3 0.9 1.0 CAI B:ZK11301 4.5 0.3 1.0 CE2 B:TYR405 4.5 0.4 1.0 CAV B:ZK11301 4.5 0.3 1.0 CAN B:ZK11301 4.7 0.3 1.0 OH B:TYR450 4.8 0.4 1.0 CB B:MET708 4.8 0.5 1.0 OE2 B:GLU705 4.8 0.9 1.0 CB B:PRO478 4.9 0.8 1.0 SD B:MET708 4.9 0.5 1.0 CAW B:ZK11301 5.0 0.3 1.0

Fluorine binding site 5 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1301 b:0.3 occ:1.00 FAG B:ZK11301 0.0 0.3 1.0 CAZ B:ZK11301 1.4 0.3 1.0 FAH B:ZK11301 2.2 0.3 1.0 FAF B:ZK11301 2.2 0.3 1.0 CAS B:ZK11301 2.3 0.3 1.0 CAJ B:ZK11301 2.7 0.3 1.0 CB B:PRO478 3.2 0.8 1.0 OH B:TYR450 3.6 0.4 1.0 CAR B:ZK11301 3.7 0.3 1.0 CG B:PRO478 3.8 0.8 1.0 OH B:TYR732 4.0 0.6 1.0 CAV B:ZK11301 4.0 0.3 1.0 CE1 B:TYR450 4.0 0.4 1.0 O B:PRO478 4.1 0.8 1.0 CE2 B:TYR732 4.2 0.6 1.0 CZ B:TYR450 4.2 0.4 1.0 CG B:GLU402 4.3 0.6 1.0 NAX B:ZK11301 4.3 0.3 1.0 CZ B:TYR732 4.3 0.6 1.0 CA B:PRO478 4.5 0.8 1.0 CE2 B:TYR405 4.5 0.4 1.0 CD2 B:TYR405 4.6 0.4 1.0 C B:PRO478 4.6 0.8 1.0 CB B:GLU402 4.6 0.6 1.0 CD B:PRO478 4.7 0.8 1.0 CAI B:ZK11301 4.8 0.3 1.0 OE1 B:GLU402 4.8 0.6 1.0 CD B:GLU402 4.8 0.6 1.0 NAP B:ZK11301 4.9 0.3 1.0 OE1 B:GLU705 4.9 0.9 1.0 CAW B:ZK11301 4.9 0.3 1.0 CAM B:ZK11301 4.9 0.3 1.0

Fluorine binding site 6 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ B:F1301 b:0.3 occ:1.00 FAH B:ZK11301 0.0 0.3 1.0 CAZ B:ZK11301 1.4 0.3 1.0 FAG B:ZK11301 2.2 0.3 1.0 FAF B:ZK11301 2.2 0.3 1.0 CAS B:ZK11301 2.4 0.3 1.0 NAX B:ZK11301 2.9 0.3 1.0 CAR B:ZK11301 3.0 0.3 1.0 OH B:TYR450 3.0 0.4 1.0 OE1 B:GLU402 3.1 0.6 1.0 CAN B:ZK11301 3.3 0.3 1.0 CAM B:ZK11301 3.4 0.3 1.0 CAL B:ZK11301 3.5 0.3 1.0 CD B:GLU402 3.5 0.6 1.0 CAK B:ZK11301 3.5 0.3 1.0 CAJ B:ZK11301 3.6 0.3 1.0 CG B:GLU402 3.8 0.6 1.0 OAQ B:ZK11301 4.1 0.3 1.0 CZ B:TYR450 4.1 0.4 1.0 CB B:GLU402 4.2 0.6 1.0 OE2 B:GLU402 4.3 0.6 1.0 CAI B:ZK11301 4.3 0.3 1.0 CE1 B:TYR450 4.7 0.4 1.0 CAV B:ZK11301 4.8 0.3 1.0 SD B:MET708 4.9 0.5 1.0 OE1 B:GLU705 5.0 0.9 1.0

Fluorine binding site 7 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ C:F1301 b:0.6 occ:1.00 FAF C:ZK11301 0.0 0.6 1.0 CAZ C:ZK11301 1.4 0.6 1.0 FAG C:ZK11301 2.2 0.6 1.0 FAH C:ZK11301 2.2 0.6 1.0 CAS C:ZK11301 2.4 0.6 1.0 OE1 C:GLU705 2.8 0.2 1.0 OH C:TYR732 3.1 0.3 1.0 CAR C:ZK11301 3.1 0.6 1.0 CAM C:ZK11301 3.3 0.6 1.0 CAJ C:ZK11301 3.3 0.6 1.0 NAX C:ZK11301 3.3 0.6 1.0 CAK C:ZK11301 3.8 0.6 1.0 CD C:GLU705 3.9 0.2 1.0 CZ C:TYR732 4.0 0.3 1.0 CE2 C:TYR732 4.2 0.3 1.0 CAI C:ZK11301 4.4 0.6 1.0 OE2 C:GLU705 4.4 0.2 1.0 CAN C:ZK11301 4.5 0.6 1.0 CAV C:ZK11301 4.5 0.6 1.0 CB C:MET708 4.8 0.7 1.0 OH C:TYR450 4.8 0.2 1.0 CAL C:ZK11301 4.9 0.6 1.0 CE2 C:TYR405 4.9 0.6 1.0 OAQ C:ZK11301 4.9 0.6 1.0 CB C:GLU705 5.0 0.2 1.0 CAW C:ZK11301 5.0 0.6 1.0

Fluorine binding site 8 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ C:F1301 b:0.6 occ:1.00 FAG C:ZK11301 0.0 0.6 1.0 CAZ C:ZK11301 1.4 0.6 1.0 FAH C:ZK11301 2.2 0.6 1.0 FAF C:ZK11301 2.2 0.6 1.0 CAS C:ZK11301 2.3 0.6 1.0 CAJ C:ZK11301 2.6 0.6 1.0 CB C:PRO478 3.3 0.2 1.0 OH C:TYR732 3.6 0.3 1.0 CAR C:ZK11301 3.7 0.6 1.0 OH C:TYR450 3.8 0.2 1.0 CE2 C:TYR732 3.9 0.3 1.0 CZ C:TYR732 4.0 0.3 1.0 CG C:PRO478 4.0 0.2 1.0 CAV C:ZK11301 4.0 0.6 1.0 O C:PRO478 4.1 0.2 1.0 CE1 C:TYR450 4.2 0.2 1.0 CZ C:TYR450 4.3 0.2 1.0 NAX C:ZK11301 4.3 0.6 1.0 OE1 C:GLU705 4.5 0.2 1.0 CA C:PRO478 4.5 0.2 1.0 C C:PRO478 4.6 0.2 1.0 CE2 C:TYR405 4.6 0.6 1.0 CG C:GLU402 4.7 0.0 1.0 CD2 C:TYR405 4.8 0.6 1.0 CAI C:ZK11301 4.8 0.6 1.0 NAP C:ZK11301 4.8 0.6 1.0 CD2 C:TYR732 4.8 0.3 1.0 CAW C:ZK11301 4.9 0.6 1.0 CD C:PRO478 4.9 0.2 1.0 CAM C:ZK11301 4.9 0.6 1.0

Fluorine binding site 9 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 9 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ C:F1301 b:0.6 occ:1.00 FAH C:ZK11301 0.0 0.6 1.0 CAZ C:ZK11301 1.4 0.6 1.0 FAG C:ZK11301 2.2 0.6 1.0 FAF C:ZK11301 2.2 0.6 1.0 CAS C:ZK11301 2.4 0.6 1.0 NAX C:ZK11301 2.9 0.6 1.0 OH C:TYR450 2.9 0.2 1.0 CAR C:ZK11301 3.0 0.6 1.0 CAN C:ZK11301 3.3 0.6 1.0 OE1 C:GLU402 3.4 0.0 1.0 CAM C:ZK11301 3.6 0.6 1.0 CAJ C:ZK11301 3.6 0.6 1.0 CAL C:ZK11301 3.6 0.6 1.0 CD C:GLU402 3.7 0.0 1.0 CAK C:ZK11301 3.8 0.6 1.0 CG C:GLU402 3.9 0.0 1.0 CZ C:TYR450 4.0 0.2 1.0 OAQ C:ZK11301 4.3 0.6 1.0 CAI C:ZK11301 4.3 0.6 1.0 CB C:GLU402 4.4 0.0 1.0 OE2 C:GLU402 4.5 0.0 1.0 CE1 C:TYR450 4.5 0.2 1.0 CAV C:ZK11301 4.7 0.6 1.0 OE1 C:GLU705 4.8 0.2 1.0 CE2 C:TYR450 4.9 0.2 1.0 OH C:TYR732 4.9 0.3 1.0

Fluorine binding site 10 out of 12 in the GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 10 of GLUA2 Bound to Antagonist Zk and GSG1L in Digitonin, State 1 within 5.0Å range: probe atom residue distance (Å) B Occ D:F1301 b:0.9 occ:1.00 FAF D:ZK11301 0.0 0.9 1.0 CAZ D:ZK11301 1.4 0.9 1.0 FAG D:ZK11301 2.2 0.9 1.0 FAH D:ZK11301 2.2 0.9 1.0 CAS D:ZK11301 2.4 0.9 1.0 OH D:TYR732 2.9 0.1 1.0 CAJ D:ZK11301 3.1 0.9 1.0 CAR D:ZK11301 3.4 0.9 1.0 OE1 D:GLU705 3.4 0.8 1.0 CE2 D:TYR732 3.5 0.1 1.0 CZ D:TYR732 3.6 0.1 1.0 CAM D:ZK11301 3.7 0.9 1.0 NAX D:ZK11301 3.8 0.9 1.0 CB D:PRO478 4.1 0.3 1.0 CAK D:ZK11301 4.3 0.9 1.0 CE2 D:TYR405 4.4 0.9 1.0 CAV D:ZK11301 4.4 0.9 1.0 CD D:GLU705 4.6 0.8 1.0 CAI D:ZK11301 4.6 0.9 1.0 OH D:TYR450 4.6 0.7 1.0 CD2 D:TYR732 4.7 0.1 1.0 CE1 D:TYR732 4.8 0.1 1.0 CG D:PRO478 4.8 0.3 1.0 CD2 D:TYR405 4.9 0.9 1.0 CAN D:ZK11301 5.0 0.9 1.0

E.C.Twomey, M.V.Yelshanskaya, R.A.Grassucci, J.Frank, A.I.Sobolevsky. Channel Opening and Gating Mechanism in Ampa-Subtype Glutamate Receptors. Nature V. 549 60 2017.
ISSN: ISSN 0028-0836
PubMed: 28737760
DOI: 10.1038/NATURE23479