|
Atomistry » Fluorine » PDB 5wfo-5xd5 » 5wjj | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 5wfo-5xd5 » 5wjj » |
Fluorine in PDB 5wjj: Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase InhibitorsEnzymatic activity of Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
All present enzymatic activity of Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors:
2.7.11.24; Protein crystallography data
The structure of Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors, PDB code: 5wjj
was solved by
G.P.Snell,
K.Okada,
K.Bragstad,
B.-C.Sang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
(pdb code 5wjj). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors, PDB code: 5wjj: Fluorine binding site 1 out of 1 in 5wjjGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
![]() Mono view ![]() Stereo pair view
Reference:
A.Kaieda,
M.Takahashi,
T.Takai,
M.Goto,
T.Miyazaki,
Y.Hori,
S.Unno,
T.Kawamoto,
T.Tanaka,
S.Itono,
T.Takagi,
T.Hamada,
M.Shirasaki,
K.Okada,
G.Snell,
K.Bragstad,
B.C.Sang,
O.Uchikawa,
S.Miwatashi.
Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors. Bioorg. Med. Chem. V. 26 647 2018.
Page generated: Tue Jul 15 09:01:18 2025
ISSN: ESSN 1464-3391 PubMed: 29291937 DOI: 10.1016/J.BMC.2017.12.031 |
Last articlesFe in 2YXOFe in 2YRS Fe in 2YXC Fe in 2YNM Fe in 2YVJ Fe in 2YP1 Fe in 2YU2 Fe in 2YU1 Fe in 2YQB Fe in 2YOO |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |