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Fluorine in PDB 5wjj: Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase InhibitorsEnzymatic activity of Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
All present enzymatic activity of Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors:
2.7.11.24; Protein crystallography data
The structure of Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors, PDB code: 5wjj
was solved by
G.P.Snell,
K.Okada,
K.Bragstad,
B.-C.Sang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
(pdb code 5wjj). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors, PDB code: 5wjj: Fluorine binding site 1 out of 1 in 5wjjGo back to Fluorine Binding Sites List in 5wjj
Fluorine binding site 1 out
of 1 in the Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors
Mono view Stereo pair view
Reference:
A.Kaieda,
M.Takahashi,
T.Takai,
M.Goto,
T.Miyazaki,
Y.Hori,
S.Unno,
T.Kawamoto,
T.Tanaka,
S.Itono,
T.Takagi,
T.Hamada,
M.Shirasaki,
K.Okada,
G.Snell,
K.Bragstad,
B.C.Sang,
O.Uchikawa,
S.Miwatashi.
Structure-Based Design, Synthesis, and Biological Evaluation of Imidazo[1,2-B]Pyridazine-Based P38 Map Kinase Inhibitors. Bioorg. Med. Chem. V. 26 647 2018.
Page generated: Sun Dec 13 12:42:05 2020
ISSN: ESSN 1464-3391 PubMed: 29291937 DOI: 10.1016/J.BMC.2017.12.031 |
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