Fluorine »
PDB 5y6d-5zab »
5yy1 »
Fluorine in PDB 5yy1: Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739
Protein crystallography data
The structure of Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739, PDB code: 5yy1
was solved by
S.Swaminathan,
M.K.Thakur,
S.Kandan,
A.Gautam,
M.Kanavalli,
P.Simhadri,
R.Gosu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 44.77 / 1.69 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 40.391, 51.730, 89.242, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 19.7 / 23.5 |
Other elements in 5yy1:
The structure of Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739 also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
| Chlorine | (Cl) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739
(pdb code 5yy1). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739, PDB code: 5yy1:
Jump to Fluorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Fluorine where determined in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739, PDB code: 5yy1:
Jump to Fluorine binding site number: 1; 2; 3; 4;
Fluorine binding site 1 out of 4 in 5yy1
Go back to
Fluorine Binding Sites List in 5yy1
Fluorine binding site 1 out
of 4 in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739 within 5.0Å range:
|
Fluorine binding site 2 out of 4 in 5yy1
Go back to
Fluorine Binding Sites List in 5yy1
Fluorine binding site 2 out
of 4 in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739 within 5.0Å range:
|
Fluorine binding site 3 out of 4 in 5yy1
Go back to
Fluorine Binding Sites List in 5yy1
Fluorine binding site 3 out
of 4 in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739 within 5.0Å range:
|
Fluorine binding site 4 out of 4 in 5yy1
Go back to
Fluorine Binding Sites List in 5yy1
Fluorine binding site 4 out
of 4 in the Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739 within 5.0Å range:
|
Reference:
S.Swaminathan,
M.K.Thakur,
S.Kandan,
A.Gautam,
M.Kanavalli,
P.Simhadri,
R.Gosu.
Co-Crystal Structure of Kras (G12C) Covalently Bound with Quinazoline Based Inhibitor JBI739 To Be Published.
Page generated: Thu Aug 1 17:23:15 2024
Last articles
Cl in 5U2PCl in 5U35
Cl in 5U27
Cl in 5U2K
Cl in 5U2A
Cl in 5U24
Cl in 5U23
Cl in 5U21
Cl in 5U1R
Cl in 5U1A
