Fluorine in PDB 6b9f: Human ATL1 Mutant - F151S Bound to GDPALF4-
Protein crystallography data
The structure of Human ATL1 Mutant - F151S Bound to GDPALF4-, PDB code: 6b9f
was solved by
J.P.O'donnell,
H.Sondermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
43.68 /
1.90
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
49.613,
115.721,
184.300,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
17.8 /
22.2
|
Other elements in 6b9f:
The structure of Human ATL1 Mutant - F151S Bound to GDPALF4- also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human ATL1 Mutant - F151S Bound to GDPALF4-
(pdb code 6b9f). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 8 binding sites of Fluorine where determined in the
Human ATL1 Mutant - F151S Bound to GDPALF4-, PDB code: 6b9f:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Fluorine binding site 1 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 1 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F507
b:22.4
occ:1.00
|
F1
|
A:ALF507
|
0.0
|
22.4
|
1.0
|
|
AL
|
A:ALF507
|
1.8
|
18.8
|
1.0
|
|
F4
|
A:ALF507
|
2.5
|
20.9
|
1.0
|
|
F3
|
A:ALF507
|
2.5
|
17.8
|
1.0
|
|
N
|
A:GLU119
|
2.5
|
17.9
|
1.0
|
|
O3B
|
A:GDP506
|
2.7
|
17.8
|
1.0
|
|
O
|
A:HOH658
|
2.8
|
17.9
|
1.0
|
|
NH2
|
A:ARG77
|
2.9
|
17.4
|
1.0
|
|
N
|
A:THR120
|
2.9
|
22.6
|
1.0
|
|
CA
|
A:GLU119
|
3.2
|
22.7
|
1.0
|
|
O
|
A:HOH677
|
3.2
|
22.8
|
1.0
|
|
CB
|
A:GLU119
|
3.2
|
22.5
|
1.0
|
|
C
|
A:GLU119
|
3.5
|
23.6
|
1.0
|
|
F2
|
A:ALF507
|
3.6
|
16.2
|
1.0
|
|
C
|
A:ARG118
|
3.6
|
21.0
|
1.0
|
|
MG
|
A:MG505
|
3.6
|
19.2
|
1.0
|
|
NE
|
A:ARG77
|
3.7
|
17.4
|
1.0
|
|
CZ
|
A:ARG77
|
3.7
|
22.1
|
1.0
|
|
CA
|
A:ARG118
|
3.9
|
22.6
|
1.0
|
|
PB
|
A:GDP506
|
4.0
|
17.5
|
1.0
|
|
OG1
|
A:THR120
|
4.0
|
15.9
|
1.0
|
|
CA
|
A:THR120
|
4.1
|
18.6
|
1.0
|
|
CB
|
A:THR120
|
4.2
|
18.1
|
1.0
|
|
O1B
|
A:GDP506
|
4.2
|
13.1
|
1.0
|
|
CB
|
A:ARG118
|
4.4
|
23.8
|
1.0
|
|
CG
|
A:GLU119
|
4.4
|
20.7
|
1.0
|
|
O
|
A:THR120
|
4.4
|
19.8
|
1.0
|
|
O2A
|
A:GDP506
|
4.5
|
20.3
|
1.0
|
|
O
|
A:GLU119
|
4.7
|
19.2
|
1.0
|
|
C
|
A:THR120
|
4.7
|
17.8
|
1.0
|
|
O3A
|
A:GDP506
|
4.7
|
15.2
|
1.0
|
|
O
|
A:ARG118
|
4.7
|
26.0
|
1.0
|
|
NH1
|
A:ARG77
|
4.9
|
16.2
|
1.0
|
|
N
|
A:ARG77
|
5.0
|
19.9
|
1.0
|
|
CD
|
A:ARG77
|
5.0
|
25.0
|
1.0
|
|
Fluorine binding site 2 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 2 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F507
b:16.2
occ:1.00
|
F2
|
A:ALF507
|
0.0
|
16.2
|
1.0
|
|
AL
|
A:ALF507
|
1.8
|
18.8
|
1.0
|
|
F3
|
A:ALF507
|
2.5
|
17.8
|
1.0
|
|
F4
|
A:ALF507
|
2.6
|
20.9
|
1.0
|
|
NZ
|
A:LYS80
|
2.6
|
15.3
|
1.0
|
|
O
|
A:HOH658
|
2.7
|
17.9
|
1.0
|
|
O3B
|
A:GDP506
|
2.7
|
17.8
|
1.0
|
|
N
|
A:GLY149
|
3.0
|
26.1
|
1.0
|
|
CA
|
A:GLY149
|
3.1
|
15.7
|
1.0
|
|
CA
|
A:PHE76
|
3.2
|
16.3
|
1.0
|
|
CB
|
A:PHE76
|
3.4
|
16.4
|
1.0
|
|
N
|
A:ARG77
|
3.4
|
19.9
|
1.0
|
|
PB
|
A:GDP506
|
3.5
|
17.5
|
1.0
|
|
O2B
|
A:GDP506
|
3.6
|
17.4
|
1.0
|
|
CE
|
A:LYS80
|
3.6
|
14.3
|
1.0
|
|
F1
|
A:ALF507
|
3.6
|
22.4
|
1.0
|
|
C
|
A:PHE76
|
3.9
|
17.4
|
1.0
|
|
O
|
A:HOH687
|
3.9
|
16.3
|
1.0
|
|
O1B
|
A:GDP506
|
4.1
|
13.1
|
1.0
|
|
C
|
A:GLN148
|
4.2
|
20.4
|
1.0
|
|
MG
|
A:MG505
|
4.2
|
19.2
|
1.0
|
|
N
|
A:PHE76
|
4.3
|
14.9
|
1.0
|
|
C
|
A:GLY149
|
4.3
|
22.0
|
1.0
|
|
O
|
A:HOH663
|
4.3
|
20.2
|
1.0
|
|
O
|
A:ALA75
|
4.4
|
15.5
|
1.0
|
|
O
|
A:THR147
|
4.5
|
19.5
|
1.0
|
|
CA
|
A:ARG77
|
4.6
|
14.4
|
1.0
|
|
C
|
A:ALA75
|
4.7
|
14.1
|
1.0
|
|
O
|
A:GLY149
|
4.7
|
16.8
|
1.0
|
|
CG
|
A:PHE76
|
4.8
|
17.9
|
1.0
|
|
CA
|
A:GLN148
|
4.8
|
17.1
|
1.0
|
|
O3A
|
A:GDP506
|
4.9
|
15.2
|
1.0
|
|
CD
|
A:LYS80
|
5.0
|
24.6
|
1.0
|
|
Fluorine binding site 3 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 3 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F507
b:17.8
occ:1.00
|
F3
|
A:ALF507
|
0.0
|
17.8
|
1.0
|
|
AL
|
A:ALF507
|
1.8
|
18.8
|
1.0
|
|
MG
|
A:MG505
|
2.0
|
19.2
|
1.0
|
|
F2
|
A:ALF507
|
2.5
|
16.2
|
1.0
|
|
F1
|
A:ALF507
|
2.5
|
22.4
|
1.0
|
|
O3B
|
A:GDP506
|
2.6
|
17.8
|
1.0
|
|
O
|
A:HOH658
|
2.7
|
17.9
|
1.0
|
|
O
|
A:HOH663
|
2.8
|
20.2
|
1.0
|
|
OG1
|
A:THR120
|
2.8
|
15.9
|
1.0
|
|
O1B
|
A:GDP506
|
2.9
|
13.1
|
1.0
|
|
CB
|
A:THR120
|
3.0
|
18.1
|
1.0
|
|
PB
|
A:GDP506
|
3.2
|
17.5
|
1.0
|
|
O
|
A:HOH677
|
3.4
|
22.8
|
1.0
|
|
N
|
A:THR120
|
3.5
|
22.6
|
1.0
|
|
F4
|
A:ALF507
|
3.5
|
20.9
|
1.0
|
|
CA
|
A:THR120
|
3.8
|
18.6
|
1.0
|
|
O
|
A:THR147
|
3.8
|
19.5
|
1.0
|
|
O2B
|
A:GDP506
|
4.0
|
17.4
|
1.0
|
|
NZ
|
A:LYS80
|
4.0
|
15.3
|
1.0
|
|
OG
|
A:SER81
|
4.1
|
21.2
|
1.0
|
|
N
|
A:GLY149
|
4.1
|
26.1
|
1.0
|
|
O
|
A:THR120
|
4.2
|
19.8
|
1.0
|
|
CG2
|
A:THR120
|
4.2
|
22.1
|
1.0
|
|
CE
|
A:LYS80
|
4.4
|
14.3
|
1.0
|
|
C
|
A:THR120
|
4.5
|
17.8
|
1.0
|
|
O3A
|
A:GDP506
|
4.6
|
15.2
|
1.0
|
|
CA
|
A:GLN148
|
4.7
|
17.1
|
1.0
|
|
C
|
A:GLU119
|
4.7
|
23.6
|
1.0
|
|
NH2
|
A:ARG77
|
4.8
|
17.4
|
1.0
|
|
N
|
A:GLU119
|
4.8
|
17.9
|
1.0
|
|
C
|
A:THR147
|
4.9
|
16.7
|
1.0
|
|
C
|
A:GLN148
|
4.9
|
20.4
|
1.0
|
|
CA
|
A:GLY149
|
4.9
|
15.7
|
1.0
|
|
Fluorine binding site 4 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 4 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F507
b:20.9
occ:1.00
|
F4
|
A:ALF507
|
0.0
|
20.9
|
1.0
|
|
AL
|
A:ALF507
|
1.8
|
18.8
|
1.0
|
|
F1
|
A:ALF507
|
2.5
|
22.4
|
1.0
|
|
F2
|
A:ALF507
|
2.6
|
16.2
|
1.0
|
|
O3B
|
A:GDP506
|
2.7
|
17.8
|
1.0
|
|
NE
|
A:ARG77
|
2.8
|
17.4
|
1.0
|
|
N
|
A:ARG77
|
2.9
|
19.9
|
1.0
|
|
O
|
A:HOH658
|
2.9
|
17.9
|
1.0
|
|
CB
|
A:PHE76
|
3.4
|
16.4
|
1.0
|
|
F3
|
A:ALF507
|
3.5
|
17.8
|
1.0
|
|
CA
|
A:ARG118
|
3.6
|
22.6
|
1.0
|
|
CA
|
A:ARG77
|
3.6
|
14.4
|
1.0
|
|
NH2
|
A:ARG77
|
3.6
|
17.4
|
1.0
|
|
CZ
|
A:ARG77
|
3.6
|
22.1
|
1.0
|
|
CD2
|
A:PHE76
|
3.7
|
23.2
|
1.0
|
|
C
|
A:PHE76
|
3.7
|
17.4
|
1.0
|
|
CD
|
A:ARG77
|
3.7
|
25.0
|
1.0
|
|
CG
|
A:ARG77
|
3.7
|
33.4
|
1.0
|
|
CA
|
A:PHE76
|
3.7
|
16.3
|
1.0
|
|
CB
|
A:ARG118
|
3.8
|
23.8
|
1.0
|
|
N
|
A:GLU119
|
3.9
|
17.9
|
1.0
|
|
CG
|
A:PHE76
|
3.9
|
17.9
|
1.0
|
|
O
|
A:HOH687
|
4.0
|
16.3
|
1.0
|
|
PB
|
A:GDP506
|
4.1
|
17.5
|
1.0
|
|
CB
|
A:ARG77
|
4.2
|
20.1
|
1.0
|
|
C
|
A:ARG118
|
4.3
|
21.0
|
1.0
|
|
N
|
A:ARG118
|
4.6
|
23.6
|
1.0
|
|
O2B
|
A:GDP506
|
4.7
|
17.4
|
1.0
|
|
O
|
A:PHE76
|
4.8
|
16.9
|
1.0
|
|
CE2
|
A:PHE76
|
4.8
|
27.4
|
1.0
|
|
NZ
|
A:LYS80
|
4.9
|
15.3
|
1.0
|
|
O3A
|
A:GDP506
|
4.9
|
15.2
|
1.0
|
|
NH1
|
A:ARG77
|
4.9
|
16.2
|
1.0
|
|
C
|
A:ARG77
|
5.0
|
17.2
|
1.0
|
|
O
|
A:GLU117
|
5.0
|
22.9
|
1.0
|
|
Fluorine binding site 5 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 5 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F507
b:23.5
occ:1.00
|
F1
|
B:ALF507
|
0.0
|
23.5
|
1.0
|
|
AL
|
B:ALF507
|
1.8
|
22.9
|
1.0
|
|
F4
|
B:ALF507
|
2.5
|
26.1
|
1.0
|
|
F3
|
B:ALF507
|
2.5
|
23.9
|
1.0
|
|
O
|
B:HOH646
|
2.7
|
20.8
|
1.0
|
|
O3B
|
B:GDP506
|
2.7
|
24.9
|
1.0
|
|
NE
|
B:ARG77
|
2.9
|
21.1
|
1.0
|
|
N
|
B:ARG77
|
2.9
|
19.6
|
1.0
|
|
CB
|
B:PHE76
|
3.3
|
25.4
|
1.0
|
|
CA
|
B:ARG118
|
3.5
|
25.6
|
1.0
|
|
F2
|
B:ALF507
|
3.6
|
25.1
|
1.0
|
|
CA
|
B:ARG77
|
3.7
|
20.2
|
1.0
|
|
CD2
|
B:PHE76
|
3.7
|
26.2
|
1.0
|
|
CG
|
B:ARG77
|
3.7
|
40.0
|
1.0
|
|
CA
|
B:PHE76
|
3.7
|
17.2
|
1.0
|
|
C
|
B:PHE76
|
3.7
|
19.3
|
1.0
|
|
CB
|
B:ARG118
|
3.7
|
25.5
|
1.0
|
|
CD
|
B:ARG77
|
3.7
|
23.7
|
1.0
|
|
O
|
B:HOH744
|
3.8
|
18.6
|
1.0
|
|
CZ
|
B:ARG77
|
3.8
|
24.2
|
1.0
|
|
NH2
|
B:ARG77
|
3.8
|
19.2
|
1.0
|
|
N
|
B:GLU119
|
3.9
|
22.7
|
1.0
|
|
CG
|
B:PHE76
|
4.0
|
20.7
|
1.0
|
|
PB
|
B:GDP506
|
4.1
|
20.5
|
1.0
|
|
CB
|
B:ARG77
|
4.2
|
26.9
|
1.0
|
|
C
|
B:ARG118
|
4.3
|
29.7
|
1.0
|
|
N
|
B:ARG118
|
4.6
|
24.3
|
1.0
|
|
O1B
|
B:GDP506
|
4.6
|
17.9
|
1.0
|
|
O
|
B:PHE76
|
4.8
|
17.8
|
1.0
|
|
NZ
|
B:LYS80
|
4.9
|
17.5
|
1.0
|
|
N
|
B:GLY149
|
4.9
|
21.4
|
1.0
|
|
CE2
|
B:PHE76
|
4.9
|
28.7
|
1.0
|
|
O
|
B:GLU117
|
4.9
|
27.2
|
1.0
|
|
CA
|
B:GLY149
|
5.0
|
21.9
|
1.0
|
|
O3A
|
B:GDP506
|
5.0
|
20.5
|
1.0
|
|
Fluorine binding site 6 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 6 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F507
b:25.1
occ:1.00
|
F2
|
B:ALF507
|
0.0
|
25.1
|
1.0
|
|
AL
|
B:ALF507
|
1.8
|
22.9
|
1.0
|
|
MG
|
B:MG505
|
1.9
|
23.4
|
1.0
|
|
F4
|
B:ALF507
|
2.5
|
26.1
|
1.0
|
|
F3
|
B:ALF507
|
2.6
|
23.9
|
1.0
|
|
O3B
|
B:GDP506
|
2.7
|
24.9
|
1.0
|
|
OG1
|
B:THR120
|
2.8
|
22.8
|
1.0
|
|
O
|
B:HOH646
|
2.8
|
20.8
|
1.0
|
|
O2B
|
B:GDP506
|
2.8
|
19.8
|
1.0
|
|
O
|
B:HOH681
|
2.8
|
20.7
|
1.0
|
|
CB
|
B:THR120
|
3.0
|
20.4
|
1.0
|
|
O
|
B:HOH665
|
3.1
|
22.4
|
1.0
|
|
PB
|
B:GDP506
|
3.1
|
20.5
|
1.0
|
|
F1
|
B:ALF507
|
3.6
|
23.5
|
1.0
|
|
N
|
B:THR120
|
3.6
|
29.0
|
1.0
|
|
CA
|
B:THR120
|
3.8
|
23.0
|
1.0
|
|
O1B
|
B:GDP506
|
3.9
|
17.9
|
1.0
|
|
O
|
B:THR147
|
3.9
|
23.9
|
1.0
|
|
NZ
|
B:LYS80
|
4.0
|
17.5
|
1.0
|
|
OG
|
B:SER81
|
4.0
|
25.2
|
1.0
|
|
N
|
B:GLY149
|
4.1
|
21.4
|
1.0
|
|
O
|
B:THR120
|
4.2
|
24.2
|
1.0
|
|
CG2
|
B:THR120
|
4.2
|
24.0
|
1.0
|
|
CE
|
B:LYS80
|
4.3
|
12.5
|
1.0
|
|
C
|
B:THR120
|
4.5
|
27.1
|
1.0
|
|
O3A
|
B:GDP506
|
4.6
|
20.5
|
1.0
|
|
C
|
B:GLU119
|
4.8
|
34.9
|
1.0
|
|
CA
|
B:GLN148
|
4.8
|
19.7
|
1.0
|
|
NH2
|
B:ARG77
|
4.8
|
19.2
|
1.0
|
|
C
|
B:GLN148
|
4.9
|
20.4
|
1.0
|
|
C
|
B:THR147
|
4.9
|
20.8
|
1.0
|
|
N
|
B:GLU119
|
4.9
|
22.7
|
1.0
|
|
CA
|
B:GLY149
|
4.9
|
21.9
|
1.0
|
|
Fluorine binding site 7 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 7 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F507
b:23.9
occ:1.00
|
F3
|
B:ALF507
|
0.0
|
23.9
|
1.0
|
|
AL
|
B:ALF507
|
1.8
|
22.9
|
1.0
|
|
F1
|
B:ALF507
|
2.5
|
23.5
|
1.0
|
|
F2
|
B:ALF507
|
2.6
|
25.1
|
1.0
|
|
NZ
|
B:LYS80
|
2.6
|
17.5
|
1.0
|
|
O
|
B:HOH646
|
2.7
|
20.8
|
1.0
|
|
O3B
|
B:GDP506
|
2.8
|
24.9
|
1.0
|
|
N
|
B:GLY149
|
2.9
|
21.4
|
1.0
|
|
CA
|
B:GLY149
|
3.0
|
21.9
|
1.0
|
|
CA
|
B:PHE76
|
3.2
|
17.2
|
1.0
|
|
N
|
B:ARG77
|
3.4
|
19.6
|
1.0
|
|
CE
|
B:LYS80
|
3.4
|
12.5
|
1.0
|
|
CB
|
B:PHE76
|
3.4
|
25.4
|
1.0
|
|
O1B
|
B:GDP506
|
3.5
|
17.9
|
1.0
|
|
PB
|
B:GDP506
|
3.6
|
20.5
|
1.0
|
|
F4
|
B:ALF507
|
3.6
|
26.1
|
1.0
|
|
O
|
B:HOH744
|
3.8
|
18.6
|
1.0
|
|
C
|
B:PHE76
|
3.8
|
19.3
|
1.0
|
|
O2B
|
B:GDP506
|
4.1
|
19.8
|
1.0
|
|
C
|
B:GLN148
|
4.2
|
20.4
|
1.0
|
|
MG
|
B:MG505
|
4.2
|
23.4
|
1.0
|
|
O
|
B:ALA75
|
4.3
|
20.3
|
1.0
|
|
C
|
B:GLY149
|
4.3
|
25.8
|
1.0
|
|
N
|
B:PHE76
|
4.3
|
18.1
|
1.0
|
|
O
|
B:HOH681
|
4.5
|
20.7
|
1.0
|
|
O
|
B:THR147
|
4.5
|
23.9
|
1.0
|
|
CA
|
B:ARG77
|
4.6
|
20.2
|
1.0
|
|
C
|
B:ALA75
|
4.7
|
18.5
|
1.0
|
|
O
|
B:GLY149
|
4.8
|
21.7
|
1.0
|
|
CG
|
B:PHE76
|
4.8
|
20.7
|
1.0
|
|
CA
|
B:GLN148
|
4.8
|
19.7
|
1.0
|
|
CD
|
B:LYS80
|
4.9
|
18.9
|
1.0
|
|
O3A
|
B:GDP506
|
5.0
|
20.5
|
1.0
|
|
Fluorine binding site 8 out
of 8 in 6b9f
Go back to
Fluorine Binding Sites List in 6b9f
Fluorine binding site 8 out
of 8 in the Human ATL1 Mutant - F151S Bound to GDPALF4-
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Human ATL1 Mutant - F151S Bound to GDPALF4- within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:F507
b:26.1
occ:1.00
|
F4
|
B:ALF507
|
0.0
|
26.1
|
1.0
|
|
AL
|
B:ALF507
|
1.8
|
22.9
|
1.0
|
|
F1
|
B:ALF507
|
2.5
|
23.5
|
1.0
|
|
F2
|
B:ALF507
|
2.5
|
25.1
|
1.0
|
|
O3B
|
B:GDP506
|
2.6
|
24.9
|
1.0
|
|
N
|
B:GLU119
|
2.7
|
22.7
|
1.0
|
|
O
|
B:HOH646
|
2.8
|
20.8
|
1.0
|
|
N
|
B:THR120
|
2.9
|
29.0
|
1.0
|
|
NH2
|
B:ARG77
|
3.0
|
19.2
|
1.0
|
|
O
|
B:HOH665
|
3.0
|
22.4
|
1.0
|
|
CB
|
B:GLU119
|
3.2
|
21.4
|
1.0
|
|
CA
|
B:GLU119
|
3.2
|
25.3
|
1.0
|
|
C
|
B:GLU119
|
3.5
|
34.9
|
1.0
|
|
MG
|
B:MG505
|
3.6
|
23.4
|
1.0
|
|
F3
|
B:ALF507
|
3.6
|
23.9
|
1.0
|
|
NE
|
B:ARG77
|
3.6
|
21.1
|
1.0
|
|
CZ
|
B:ARG77
|
3.7
|
24.2
|
1.0
|
|
C
|
B:ARG118
|
3.8
|
29.7
|
1.0
|
|
PB
|
B:GDP506
|
3.8
|
20.5
|
1.0
|
|
OG1
|
B:THR120
|
3.8
|
22.8
|
1.0
|
|
CA
|
B:ARG118
|
4.0
|
25.6
|
1.0
|
|
CA
|
B:THR120
|
4.1
|
23.0
|
1.0
|
|
O2B
|
B:GDP506
|
4.1
|
19.8
|
1.0
|
|
CB
|
B:THR120
|
4.1
|
20.4
|
1.0
|
|
O
|
B:THR120
|
4.4
|
24.2
|
1.0
|
|
CG
|
B:GLU119
|
4.4
|
26.2
|
1.0
|
|
CB
|
B:ARG118
|
4.4
|
25.5
|
1.0
|
|
O1A
|
B:GDP506
|
4.5
|
20.6
|
1.0
|
|
O3A
|
B:GDP506
|
4.6
|
20.5
|
1.0
|
|
O
|
B:GLU119
|
4.7
|
28.7
|
1.0
|
|
C
|
B:THR120
|
4.7
|
27.1
|
1.0
|
|
O
|
B:ARG118
|
4.9
|
25.7
|
1.0
|
|
N
|
B:ARG77
|
4.9
|
19.6
|
1.0
|
|
CD
|
B:ARG77
|
4.9
|
23.7
|
1.0
|
|
NH1
|
B:ARG77
|
4.9
|
19.8
|
1.0
|
|
O1B
|
B:GDP506
|
5.0
|
17.9
|
1.0
|
|
Reference:
J.P.O'donnell,
L.J.Byrnes,
R.B.Cooley,
H.Sondermann.
A Hereditary Spastic Paraplegia-Associated Atlastin Variant Exhibits Defective Allosteric Coupling in the Catalytic Core. J. Biol. Chem. V. 293 687 2018.
ISSN: ESSN 1083-351X
PubMed: 29180453
DOI: 10.1074/JBC.RA117.000380
Page generated: Thu Aug 1 18:01:06 2024
|
