Fluorine in PDB 6bpr: Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase
Enzymatic activity of Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase
All present enzymatic activity of Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase:
1.13.11.20;
1.13.11.20;
Protein crystallography data
The structure of Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase, PDB code: 6bpr
was solved by
A.Liu,
J.Li,
I.Shin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 32.83 / 1.96 |
| Space group | P 65 |
| Cell size a, b, c (Å), α, β, γ (°) | 131.306, 131.306, 34.175, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 16.1 / 18.8 |
Other elements in 6bpr:
The structure of Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase also contains other interesting chemical elements:
| Iron | (Fe) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase
(pdb code 6bpr). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase, PDB code: 6bpr:
Jump to Fluorine binding site number: 1; 2;
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase, PDB code: 6bpr:
Jump to Fluorine binding site number: 1; 2;
Fluorine binding site 1 out of 2 in 6bpr
Go back to
Fluorine Binding Sites List in 6bpr
Fluorine binding site 1 out
of 2 in the Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase within 5.0Å range:
|
Fluorine binding site 2 out of 2 in 6bpr
Go back to
Fluorine Binding Sites List in 6bpr
Fluorine binding site 2 out
of 2 in the Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Cysteine, Nitric Oxide-Bound Ferrous Form of the Uncrosslinked F2-TYR157 Human Cysteine Dioxygenase within 5.0Å range:
|
Reference:
J.Li,
T.Koto,
I.Davis,
A.Liu.
Probing the Cys-Tyr Cofactor Biogenesis in Cysteine Dioxygenase By the Genetic Incorporation of Fluorotyrosine. Biochemistry V. 58 2218 2019.
ISSN: ISSN 0006-2960
PubMed: 30946568
DOI: 10.1021/ACS.BIOCHEM.9B00006
Page generated: Sun Dec 13 12:45:42 2020
ISSN: ISSN 0006-2960
PubMed: 30946568
DOI: 10.1021/ACS.BIOCHEM.9B00006
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