Fluorine in PDB 6bq1: Human PI4KIIIA Lipid Kinase Complex

Enzymatic activity of Human PI4KIIIA Lipid Kinase Complex

All present enzymatic activity of Human PI4KIIIA Lipid Kinase Complex:
2.7.1.67;

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Human PI4KIIIA Lipid Kinase Complex (pdb code 6bq1). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Human PI4KIIIA Lipid Kinase Complex, PDB code: 6bq1:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in 6bq1

Go back to Fluorine Binding Sites List in 6bq1
Fluorine binding site 1 out of 2 in the Human PI4KIIIA Lipid Kinase Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Human PI4KIIIA Lipid Kinase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F2201

b:77.1
occ:1.00
F01 A:E4S2201 0.0 77.1 1.0
C29 A:E4S2201 1.4 77.1 1.0
C28 A:E4S2201 2.3 77.1 1.0
C24 A:E4S2201 2.5 77.1 1.0
H27 A:E4S2201 2.5 77.1 1.0
OD1 A:ASN1962 2.6 1.0 1.0
O04 A:E4S2201 2.7 77.1 1.0
N06 A:E4S2201 2.9 77.1 1.0
S01 A:E4S2201 3.3 77.1 1.0
H23 A:E4S2201 3.4 77.1 1.0
C25 A:E4S2201 3.7 77.1 1.0
CG A:ASN1962 3.7 1.0 1.0
C27 A:E4S2201 3.7 77.1 1.0
O03 A:E4S2201 3.9 77.1 1.0
ND2 A:ASN1962 4.1 1.0 1.0
C26 A:E4S2201 4.2 77.1 1.0
H24 A:E4S2201 4.4 77.1 1.0
H26 A:E4S2201 4.5 77.1 1.0
O A:SER1797 4.9 0.2 1.0
C03 A:E4S2201 4.9 77.1 1.0
CB A:ASN1962 5.0 1.0 1.0

Fluorine binding site 2 out of 2 in 6bq1

Go back to Fluorine Binding Sites List in 6bq1
Fluorine binding site 2 out of 2 in the Human PI4KIIIA Lipid Kinase Complex


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Human PI4KIIIA Lipid Kinase Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
E:F2201

b:66.5
occ:1.00
F01 E:E4S2201 0.0 66.5 1.0
C29 E:E4S2201 1.4 66.5 1.0
C28 E:E4S2201 2.3 66.5 1.0
C24 E:E4S2201 2.5 66.5 1.0
H27 E:E4S2201 2.5 66.5 1.0
O04 E:E4S2201 2.6 66.5 1.0
OD1 E:ASN1962 2.9 0.9 1.0
N06 E:E4S2201 2.9 66.5 1.0
S01 E:E4S2201 3.3 66.5 1.0
H23 E:E4S2201 3.4 66.5 1.0
C25 E:E4S2201 3.7 66.5 1.0
C27 E:E4S2201 3.7 66.5 1.0
CG E:ASN1962 4.0 0.9 1.0
O03 E:E4S2201 4.2 66.5 1.0
C26 E:E4S2201 4.2 66.5 1.0
H24 E:E4S2201 4.4 66.5 1.0
H26 E:E4S2201 4.5 66.5 1.0
ND2 E:ASN1962 4.6 0.9 1.0
C03 E:E4S2201 4.6 66.5 1.0
O E:SER1797 4.9 0.6 1.0

Reference:

J.A.Lees, Y.Zhang, M.S.Oh, C.M.Schauder, X.Yu, J.M.Baskin, K.Dobbs, L.D.Notarangelo, P.De Camilli, T.Walz, K.M.Reinisch. Architecture of the Human PI4KIII Alpha Lipid Kinase Complex. Proc. Natl. Acad. Sci. V. 114 13720 2017U.S.A..
ISSN: ESSN 1091-6490
PubMed: 29229838
DOI: 10.1073/PNAS.1718471115
Page generated: Sun Dec 13 12:45:53 2020

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