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Fluorine in PDB 6c2r: Aurora A Ligand ComplexEnzymatic activity of Aurora A Ligand Complex
All present enzymatic activity of Aurora A Ligand Complex:
2.7.11.1; Protein crystallography data
The structure of Aurora A Ligand Complex, PDB code: 6c2r
was solved by
S.Antonysamy,
A.Pustilnik,
D.Manglicmot,
K.Froning,
K.Weichert,
S.Wasserman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6c2r:
The structure of Aurora A Ligand Complex also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Aurora A Ligand Complex
(pdb code 6c2r). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Aurora A Ligand Complex, PDB code: 6c2r: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 6c2rGo back to Fluorine Binding Sites List in 6c2r
Fluorine binding site 1 out
of 2 in the Aurora A Ligand Complex
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 6c2rGo back to Fluorine Binding Sites List in 6c2r
Fluorine binding site 2 out
of 2 in the Aurora A Ligand Complex
Mono view Stereo pair view
Reference:
X.Gong,
J.Du,
S.H.Parsons,
F.F.Merzoug,
Y.Webster,
P.W.Iversen,
L.C.Chio,
R.D.Van Horn,
X.Lin,
W.Blosser,
B.Han,
S.Jin,
S.Yao,
H.Bian,
C.Ficklin,
L.Fan,
A.Kapoor,
S.Antonysamy,
A.M.Mc Nulty,
K.Froning,
D.Manglicmot,
A.Pustilnik,
K.Weichert,
S.R.Wasserman,
M.Dowless,
C.Marugan,
C.Baquero,
M.J.Lallena,
S.W.Eastman,
Y.H.Hui,
M.Z.Dieter,
T.Doman,
S.Chu,
H.R.Qian,
X.S.Ye,
D.A.Barda,
G.D.Plowman,
C.Reinhard,
R.M.Campbell,
J.R.Henry,
S.G.Buchanan.
Aurora A Kinase Inhibition Is Synthetic Lethal with Loss of THERB1TUMOR Suppressor Gene. Cancer Discov V. 9 248 2019.
Page generated: Sun Dec 13 12:46:16 2020
ISSN: ESSN 2159-8290 PubMed: 30373917 DOI: 10.1158/2159-8290.CD-18-0469 |
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