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Fluorine in PDB 6c2y: Human GRK2 in Complex with Gbetagamma Subunits and CCG257142Enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG257142
All present enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG257142:
2.7.11.15; Protein crystallography data
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG257142, PDB code: 6c2y
was solved by
R.Bouley,
J.J.G.Tesmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human GRK2 in Complex with Gbetagamma Subunits and CCG257142
(pdb code 6c2y). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human GRK2 in Complex with Gbetagamma Subunits and CCG257142, PDB code: 6c2y: Fluorine binding site 1 out of 1 in 6c2yGo back to Fluorine Binding Sites List in 6c2y
Fluorine binding site 1 out
of 1 in the Human GRK2 in Complex with Gbetagamma Subunits and CCG257142
Mono view Stereo pair view
Reference:
H.V.Waldschmidt,
R.Bouley,
P.D.Kirchhoff,
P.Lee,
J.J.G.Tesmer,
S.D.Larsen.
Utilizing A Structure-Based Docking Approach to Develop Potent G Protein-Coupled Receptor Kinase (Grk) 2 and 5 Inhibitors. Bioorg. Med. Chem. Lett. V. 28 1507 2018.
Page generated: Sun Dec 13 12:46:20 2020
ISSN: ESSN 1464-3405 PubMed: 29627263 DOI: 10.1016/J.BMCL.2018.03.082 |
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