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Atomistry » Fluorine » PDB 6c0t-6cqh » 6ccs | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6c0t-6cqh » 6ccs » |
Fluorine in PDB 6ccs: Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-OlEnzymatic activity of Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
All present enzymatic activity of Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol:
2.7.7.3; Protein crystallography data
The structure of Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol, PDB code: 6ccs
was solved by
M.Mamo,
B.A.Appleton,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
(pdb code 6ccs). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol, PDB code: 6ccs: Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; Fluorine binding site 1 out of 6 in 6ccsGo back to Fluorine Binding Sites List in 6ccs
Fluorine binding site 1 out
of 6 in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
Mono view Stereo pair view
Fluorine binding site 2 out of 6 in 6ccsGo back to Fluorine Binding Sites List in 6ccs
Fluorine binding site 2 out
of 6 in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
Mono view Stereo pair view
Fluorine binding site 3 out of 6 in 6ccsGo back to Fluorine Binding Sites List in 6ccs
Fluorine binding site 3 out
of 6 in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
Mono view Stereo pair view
Fluorine binding site 4 out of 6 in 6ccsGo back to Fluorine Binding Sites List in 6ccs
Fluorine binding site 4 out
of 6 in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
Mono view Stereo pair view
Fluorine binding site 5 out of 6 in 6ccsGo back to Fluorine Binding Sites List in 6ccs
Fluorine binding site 5 out
of 6 in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
Mono view Stereo pair view
Fluorine binding site 6 out of 6 in 6ccsGo back to Fluorine Binding Sites List in 6ccs
Fluorine binding site 6 out
of 6 in the Crystal Structure of E.Coli Phosphopantetheine Adenylyltransferase (Ppat/Coad) in Complex with 2-(Trifluoromethyl)-1H-Benzo[D]Imidazol- 4-Ol
Mono view Stereo pair view
Reference:
R.J.Moreau,
C.K.Skepper,
B.A.Appleton,
A.Blechschmidt,
C.J.Balibar,
B.M.Benton,
J.E.Drumm,
B.Y.Feng,
M.Geng,
C.Li,
M.K.Lindvall,
A.Lingel,
Y.Lu,
M.Mamo,
W.Mergo,
V.Polyakov,
T.M.Smith,
K.Takeoka,
K.Uehara,
L.Wang,
J.R.Wei,
A.H.Weiss,
L.Xie,
W.Xu,
Q.Zhang,
J.De Vicente.
Fragment-Based Drug Discovery of Inhibitors of Phosphopantetheine Adenylyltransferase From Gram-Negative Bacteria. J. Med. Chem. V. 61 3309 2018.
Page generated: Thu Aug 1 18:30:27 2024
ISSN: ISSN 1520-4804 PubMed: 29498517 DOI: 10.1021/ACS.JMEDCHEM.7B01691 |
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