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Fluorine in PDB 6cur: Ras:Sos:Ras in Complex with A Small Molecule ActivatorProtein crystallography data
The structure of Ras:Sos:Ras in Complex with A Small Molecule Activator, PDB code: 6cur
was solved by
J.Phan,
J.Abbott,
S.W.Fesik,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6cur:
The structure of Ras:Sos:Ras in Complex with A Small Molecule Activator also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Ras:Sos:Ras in Complex with A Small Molecule Activator
(pdb code 6cur). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Ras:Sos:Ras in Complex with A Small Molecule Activator, PDB code: 6cur: Fluorine binding site 1 out of 1 in 6curGo back to Fluorine Binding Sites List in 6cur
Fluorine binding site 1 out
of 1 in the Ras:Sos:Ras in Complex with A Small Molecule Activator
Mono view Stereo pair view
Reference:
J.R.Abbott,
P.A.Patel,
J.E.Howes,
D.T.Akan,
J.P.Kennedy,
M.C.Burns,
C.F.Browning,
Q.Sun,
O.W.Rossanese,
J.Phan,
A.G.Waterson,
S.W.Fesik.
Discovery of Quinazolines That Activate SOS1-Mediated Nucleotide Exchange on Ras. Acs Med Chem Lett V. 9 941 2018.
Page generated: Sun Dec 13 12:47:06 2020
ISSN: ISSN 1948-5875 PubMed: 30258545 DOI: 10.1021/ACSMEDCHEMLETT.8B00296 |
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