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Fluorine in PDB 6fyz: Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase InhibitorEnzymatic activity of Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor
All present enzymatic activity of Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor:
3.5.1.98; Protein crystallography data
The structure of Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor, PDB code: 6fyz
was solved by
C.A.Luckhurst,
M.C.Maillard,
C.Dominguez,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6fyz:
The structure of Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor
(pdb code 6fyz). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor, PDB code: 6fyz: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 6fyzGo back to Fluorine Binding Sites List in 6fyz
Fluorine binding site 1 out
of 3 in the Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 6fyzGo back to Fluorine Binding Sites List in 6fyz
Fluorine binding site 2 out
of 3 in the Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 6fyzGo back to Fluorine Binding Sites List in 6fyz
Fluorine binding site 3 out
of 3 in the Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor
Mono view Stereo pair view
Reference:
C.A.Luckhurst,
O.Aziz,
V.Beaumont,
R.W.Burli,
P.Breccia,
M.C.Maillard,
A.F.Haughan,
M.Lamers,
P.Leonard,
K.L.Matthews,
G.Raphy,
A.J.Stott,
I.Munoz-Sanjuan,
B.Thomas,
M.Wall,
G.Wishart,
D.Yates,
C.Dominguez.
Development and Characterization of A Cns-Penetrant Benzhydryl Hydroxamic Acid Class Iia Histone Deacetylase Inhibitor. Bioorg. Med. Chem. Lett. V. 29 83 2019.
Page generated: Sun Dec 13 12:50:51 2020
ISSN: ESSN 1464-3405 PubMed: 30463802 DOI: 10.1016/J.BMCL.2018.11.009 |
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