Fluorine »
PDB 6gqm-6hax »
6haw »
Fluorine in PDB 6haw: Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7
Enzymatic activity of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7
All present enzymatic activity of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7:
1.10.2.2;
1.10.2.2;
Protein crystallography data
The structure of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7, PDB code: 6haw
was solved by
K.Amporndanai,
W.D.Hong,
P.M.O'neill,
S.S.Hasnain,
S.V.Antonyuk,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 92.10 / 3.45 |
| Space group | P 65 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 212.690, 212.690, 347.066, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 21 / 24.2 |
Other elements in 6haw:
The structure of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7 also contains other interesting chemical elements:
| Iron | (Fe) | 5 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7
(pdb code 6haw). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7, PDB code: 6haw:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7, PDB code: 6haw:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 6haw
Go back to
Fluorine Binding Sites List in 6haw
Fluorine binding site 1 out
of 3 in the Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7 within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 6haw
Go back to
Fluorine Binding Sites List in 6haw
Fluorine binding site 2 out
of 3 in the Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7 within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 6haw
Go back to
Fluorine Binding Sites List in 6haw
Fluorine binding site 3 out
of 3 in the Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Bovine Cytochrome BC1 in Complex with 2-Pyrazolyl Quinolone Inhibitor WDH2G7 within 5.0Å range:
|
Reference:
W.David Hong,
S.C.Leung,
K.Amporndanai,
J.Davies,
R.S.Priestley,
G.L.Nixon,
N.G.Berry,
S.Samar Hasnain,
S.Antonyuk,
S.A.Ward,
G.A.Biagini,
P.M.O'neill.
Potent Antimalarial 2-Pyrazolyl QUINOLONEBC1(Qi) Inhibitors with Improved Drug-Like Properties. Acs Med Chem Lett V. 9 1205 2018.
ISSN: ISSN 1948-5875
PubMed: 30613327
DOI: 10.1021/ACSMEDCHEMLETT.8B00371
Page generated: Thu Aug 1 20:57:05 2024
ISSN: ISSN 1948-5875
PubMed: 30613327
DOI: 10.1021/ACSMEDCHEMLETT.8B00371
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
