Fluorine in PDB 6hoo: Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase

All present enzymatic activity of Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase:
3.5.2.6;

The structure of Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase, PDB code: 6hoo was solved by A.Zavala, P.Retailleau, L.Dabos, T.Naas, B.Iorga, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.78 / 2.38
Space group	P 21 3
Cell size a, b, c (Å), α, β, γ (°)	126.650, 126.650, 126.650, 90.00, 90.00, 90.00
R / Rfree (%)	17.1 / 21.4

The binding sites of Fluorine atom in the Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase (pdb code 6hoo). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase, PDB code: 6hoo:

Fluorine binding site 1 out of 1 in the Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of Rationally Designed Oxa-48LOOP18 Beta-Lactamase within 5.0Å range: probe atom residue distance (Å) B Occ B:F310 b:68.0 occ:0.33 CD B:LYS94 3.8 53.4 1.0 NZ B:LYS94 4.0 73.5 1.0 CE B:LYS94 4.4 59.9 1.0 CG B:LYS94 5.0 51.9 1.0

L.Dabos, A.Zavala, L.Dortet, R.A.Bonnin, O.Beckstein, P.Retailleau, B.I.Iorga, T.Naas. Substrate Specificity of Oxa-48 Modified By Beta-5-Beta-6 Loop Replacement To Be Published.