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Atomistry » Fluorine » PDB 6hmr-6i78 » 6hwt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6hmr-6i78 » 6hwt » |
Fluorine in PDB 6hwt: Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31)Enzymatic activity of Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31)
All present enzymatic activity of Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31):
2.7.11.24; Protein crystallography data
The structure of Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31), PDB code: 6hwt
was solved by
M.P.Mueller,
D.Rauh,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31)
(pdb code 6hwt). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31), PDB code: 6hwt: Fluorine binding site 1 out of 1 in 6hwtGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Crystal Structure of P38ALPHA in Complex with A Reduced Photoswitchable 2-Azothiazol-Based Inhibitor (Compound 31)
![]() Mono view ![]() Stereo pair view
Reference:
M.Schehr,
C.Ianes,
J.Weisner,
L.Heintze,
M.P.Muller,
C.Pichlo,
J.Charl,
E.Brunstein,
J.Ewert,
M.Lehr,
U.Baumann,
D.Rauh,
U.Knippschild,
C.Peifer,
R.Herges.
2-Azo-, 2-Diazocine-Thiazols and 2-Azo-Imidazoles As Photoswitchable Kinase Inhibitors: Limitations and Pitfalls of the Photoswitchable Inhibitor Approach. Photochem. Photobiol. Sci. V. 18 1398 2019.
Page generated: Tue Jul 15 12:26:16 2025
ISSN: ISSN 1474-9092 PubMed: 30924488 DOI: 10.1039/C9PP00010K |
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