Fluorine in PDB 6kc6: Hoip-HOIPIN8 Complex
Enzymatic activity of Hoip-HOIPIN8 Complex
All present enzymatic activity of Hoip-HOIPIN8 Complex:
2.3.2.31;
Protein crystallography data
The structure of Hoip-HOIPIN8 Complex, PDB code: 6kc6
was solved by
Y.Sato,
S.Fukai,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
46.59 /
2.12
|
|
Space group
|
C 1 2 1
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
151.586,
88.793,
104.438,
90.00,
101.08,
90.00
|
|
R / Rfree (%)
|
21.1 /
26.7
|
Other elements in 6kc6:
The structure of Hoip-HOIPIN8 Complex also contains other interesting chemical elements:
Fluorine Binding Sites:
Pages:
>>> Page 1 <<<
Page 2, Binding sites: 11 -
12;
Binding sites:
The binding sites of Fluorine atom in the Hoip-HOIPIN8 Complex
(pdb code 6kc6). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 12 binding sites of Fluorine where determined in the
Hoip-HOIPIN8 Complex, PDB code: 6kc6:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
10;
Fluorine binding site 1 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 1 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1105
b:58.6
occ:1.00
|
F1
|
A:D601105
|
0.0
|
58.6
|
1.0
|
|
C19
|
A:D601105
|
1.3
|
51.3
|
1.0
|
|
C20
|
A:D601105
|
2.3
|
45.1
|
1.0
|
|
C15
|
A:D601105
|
2.4
|
51.3
|
1.0
|
|
O
|
A:GLY884
|
2.8
|
74.8
|
1.0
|
|
C13
|
A:D601105
|
2.9
|
52.6
|
1.0
|
|
C14
|
A:D601105
|
2.9
|
57.2
|
1.0
|
|
C15
|
I:D601105
|
3.1
|
51.8
|
1.0
|
|
C19
|
I:D601105
|
3.2
|
45.2
|
1.0
|
|
F1
|
I:D601105
|
3.3
|
53.2
|
1.0
|
|
C14
|
I:D601105
|
3.3
|
57.6
|
1.0
|
|
C12
|
A:D601105
|
3.3
|
51.1
|
1.0
|
|
O3
|
I:D601105
|
3.5
|
59.5
|
1.0
|
|
CB
|
A:CYS885
|
3.5
|
54.8
|
1.0
|
|
C
|
A:GLY884
|
3.5
|
69.7
|
1.0
|
|
C18
|
A:D601105
|
3.6
|
44.3
|
1.0
|
|
C16
|
A:D601105
|
3.6
|
47.7
|
1.0
|
|
CA
|
A:CYS885
|
3.6
|
59.4
|
1.0
|
|
C16
|
I:D601105
|
3.8
|
55.8
|
1.0
|
|
C20
|
I:D601105
|
3.8
|
43.8
|
1.0
|
|
N
|
A:CYS885
|
4.0
|
60.8
|
1.0
|
|
O3
|
A:D601105
|
4.0
|
64.2
|
1.0
|
|
C17
|
A:D601105
|
4.1
|
43.4
|
1.0
|
|
SG
|
A:CYS885
|
4.2
|
54.4
|
1.0
|
|
O2
|
A:D601105
|
4.3
|
42.3
|
1.0
|
|
C13
|
I:D601105
|
4.3
|
58.6
|
1.0
|
|
C17
|
I:D601105
|
4.3
|
50.4
|
1.0
|
|
F2
|
I:D601105
|
4.4
|
62.9
|
1.0
|
|
C18
|
I:D601105
|
4.4
|
47.5
|
1.0
|
|
C4
|
A:D601105
|
4.6
|
48.1
|
1.0
|
|
CA
|
A:GLY884
|
4.6
|
71.8
|
1.0
|
|
C21
|
A:D601105
|
4.7
|
45.5
|
1.0
|
|
F2
|
A:D601105
|
4.7
|
55.2
|
1.0
|
|
O
|
A:GLY883
|
4.8
|
84.7
|
1.0
|
|
C11
|
A:D601105
|
4.9
|
45.1
|
1.0
|
|
O3
|
A:GOL1109
|
4.9
|
60.2
|
1.0
|
|
Fluorine binding site 2 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 2 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F1105
b:55.2
occ:1.00
|
F2
|
A:D601105
|
0.0
|
55.2
|
1.0
|
|
C16
|
A:D601105
|
1.4
|
47.7
|
1.0
|
|
C15
|
A:D601105
|
2.4
|
51.3
|
1.0
|
|
C17
|
A:D601105
|
2.4
|
43.4
|
1.0
|
|
O3
|
A:D601105
|
2.5
|
64.2
|
1.0
|
|
C14
|
A:D601105
|
2.7
|
57.2
|
1.0
|
|
O1
|
A:D601105
|
3.4
|
46.8
|
1.0
|
|
O
|
A:HOH1210
|
3.5
|
43.7
|
1.0
|
|
C19
|
A:D601105
|
3.6
|
51.3
|
1.0
|
|
C18
|
A:D601105
|
3.6
|
44.3
|
1.0
|
|
C11
|
A:D601105
|
3.6
|
45.1
|
1.0
|
|
C3
|
A:D601105
|
3.9
|
46.1
|
1.0
|
|
C13
|
A:D601105
|
4.1
|
52.6
|
1.0
|
|
C20
|
A:D601105
|
4.1
|
45.1
|
1.0
|
|
CL
|
I:CL1107
|
4.2
|
86.5
|
1.0
|
|
C4
|
A:D601105
|
4.2
|
48.1
|
1.0
|
|
O2
|
A:D601105
|
4.2
|
42.3
|
1.0
|
|
C12
|
A:D601105
|
4.4
|
51.1
|
1.0
|
|
C5
|
A:D601105
|
4.5
|
44.8
|
1.0
|
|
F1
|
I:D601105
|
4.6
|
53.2
|
1.0
|
|
F1
|
A:D601105
|
4.7
|
58.6
|
1.0
|
|
C21
|
A:D601105
|
4.7
|
45.5
|
1.0
|
|
O
|
I:GLY884
|
4.8
|
69.6
|
1.0
|
|
NH1
|
A:ARG935
|
4.8
|
40.0
|
1.0
|
|
O
|
A:HOH1264
|
4.9
|
53.4
|
1.0
|
|
C20
|
I:D601105
|
4.9
|
43.8
|
1.0
|
|
CA
|
I:GLY884
|
5.0
|
63.2
|
1.0
|
|
Fluorine binding site 3 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 3 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F1105
b:54.6
occ:1.00
|
F1
|
C:D601105
|
0.0
|
54.6
|
1.0
|
|
C19
|
C:D601105
|
1.3
|
52.3
|
1.0
|
|
C20
|
C:D601105
|
2.3
|
46.9
|
1.0
|
|
C15
|
C:D601105
|
2.3
|
56.6
|
1.0
|
|
C14
|
C:D601105
|
2.8
|
62.4
|
1.0
|
|
C13
|
C:D601105
|
2.9
|
59.0
|
1.0
|
|
O
|
C:GLY884
|
2.9
|
68.4
|
1.0
|
|
F1
|
K:D601105
|
3.1
|
53.4
|
1.0
|
|
C19
|
K:D601105
|
3.1
|
50.0
|
1.0
|
|
C15
|
K:D601105
|
3.2
|
55.3
|
1.0
|
|
C12
|
C:D601105
|
3.2
|
51.2
|
1.0
|
|
C14
|
K:D601105
|
3.3
|
56.1
|
1.0
|
|
CB
|
C:CYS885
|
3.4
|
57.3
|
1.0
|
|
CA
|
C:CYS885
|
3.5
|
59.2
|
1.0
|
|
C18
|
C:D601105
|
3.6
|
52.4
|
1.0
|
|
C16
|
C:D601105
|
3.6
|
60.1
|
1.0
|
|
O3
|
K:D601105
|
3.6
|
55.2
|
1.0
|
|
C
|
C:GLY884
|
3.6
|
62.0
|
1.0
|
|
N
|
C:CYS885
|
3.9
|
61.2
|
1.0
|
|
C20
|
K:D601105
|
3.9
|
48.9
|
1.0
|
|
O3
|
C:D601105
|
3.9
|
68.8
|
1.0
|
|
C13
|
K:D601105
|
4.0
|
52.9
|
1.0
|
|
C16
|
K:D601105
|
4.0
|
58.5
|
1.0
|
|
C17
|
C:D601105
|
4.0
|
58.3
|
1.0
|
|
SG
|
C:CYS885
|
4.1
|
54.3
|
1.0
|
|
O2
|
C:D601105
|
4.1
|
44.9
|
1.0
|
|
C4
|
C:D601105
|
4.5
|
47.6
|
1.0
|
|
F2
|
C:D601105
|
4.6
|
64.0
|
1.0
|
|
C18
|
K:D601105
|
4.6
|
52.7
|
1.0
|
|
C21
|
C:D601105
|
4.6
|
50.6
|
1.0
|
|
C17
|
K:D601105
|
4.7
|
55.6
|
1.0
|
|
F2
|
K:D601105
|
4.7
|
60.9
|
1.0
|
|
C11
|
C:D601105
|
4.7
|
44.2
|
1.0
|
|
CA
|
C:GLY884
|
4.8
|
61.3
|
1.0
|
|
C
|
C:CYS885
|
4.9
|
58.3
|
1.0
|
|
C23
|
C:D601105
|
5.0
|
43.8
|
1.0
|
|
Fluorine binding site 4 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 4 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F1105
b:64.0
occ:1.00
|
F2
|
C:D601105
|
0.0
|
64.0
|
1.0
|
|
C16
|
C:D601105
|
1.3
|
60.1
|
1.0
|
|
C15
|
C:D601105
|
2.3
|
56.6
|
1.0
|
|
C17
|
C:D601105
|
2.4
|
58.3
|
1.0
|
|
O3
|
C:D601105
|
2.5
|
68.8
|
1.0
|
|
C14
|
C:D601105
|
2.7
|
62.4
|
1.0
|
|
O2
|
K:GOL1107
|
2.7
|
77.2
|
1.0
|
|
O
|
C:HOH1208
|
3.5
|
54.4
|
1.0
|
|
O1
|
C:D601105
|
3.5
|
42.7
|
1.0
|
|
C19
|
C:D601105
|
3.6
|
52.3
|
1.0
|
|
C18
|
C:D601105
|
3.6
|
52.4
|
1.0
|
|
C11
|
C:D601105
|
3.8
|
44.2
|
1.0
|
|
C3
|
C:D601105
|
4.0
|
44.0
|
1.0
|
|
C13
|
C:D601105
|
4.1
|
59.0
|
1.0
|
|
C20
|
C:D601105
|
4.1
|
46.9
|
1.0
|
|
C2
|
K:GOL1107
|
4.1
|
78.8
|
1.0
|
|
C4
|
C:D601105
|
4.3
|
47.6
|
1.0
|
|
O2
|
C:D601105
|
4.4
|
44.9
|
1.0
|
|
C12
|
C:D601105
|
4.4
|
51.2
|
1.0
|
|
CA
|
K:GLY884
|
4.4
|
66.6
|
1.0
|
|
F1
|
K:D601105
|
4.5
|
53.4
|
1.0
|
|
C5
|
C:D601105
|
4.6
|
45.1
|
1.0
|
|
C3
|
K:GOL1107
|
4.6
|
77.9
|
1.0
|
|
F1
|
C:D601105
|
4.6
|
54.6
|
1.0
|
|
C21
|
C:D601105
|
4.7
|
50.6
|
1.0
|
|
C1
|
K:GOL1107
|
4.9
|
78.9
|
1.0
|
|
NH1
|
C:ARG935
|
5.0
|
38.5
|
1.0
|
|
Fluorine binding site 5 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 5 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F1105
b:71.8
occ:1.00
|
F1
|
E:D601105
|
0.0
|
71.8
|
1.0
|
|
C19
|
E:D601105
|
1.2
|
67.0
|
1.0
|
|
C20
|
E:D601105
|
2.3
|
62.4
|
1.0
|
|
C15
|
E:D601105
|
2.3
|
70.2
|
1.0
|
|
O
|
E:GLY884
|
2.5
|
70.0
|
1.0
|
|
C13
|
E:D601105
|
2.8
|
69.2
|
1.0
|
|
C14
|
E:D601105
|
2.9
|
71.7
|
1.0
|
|
C12
|
E:D601105
|
3.2
|
67.5
|
1.0
|
|
CB
|
E:CYS885
|
3.3
|
57.8
|
1.0
|
|
CA
|
E:CYS885
|
3.4
|
58.2
|
1.0
|
|
C
|
E:GLY884
|
3.4
|
68.3
|
1.0
|
|
C18
|
E:D601105
|
3.5
|
62.9
|
1.0
|
|
C16
|
E:D601105
|
3.6
|
66.7
|
1.0
|
|
N
|
E:CYS885
|
3.8
|
63.6
|
1.0
|
|
SG
|
E:CYS885
|
4.0
|
61.0
|
1.0
|
|
C17
|
E:D601105
|
4.0
|
62.0
|
1.0
|
|
O3
|
E:D601105
|
4.1
|
71.2
|
1.0
|
|
O2
|
E:D601105
|
4.1
|
54.9
|
1.0
|
|
C4
|
E:D601105
|
4.4
|
65.8
|
1.0
|
|
C21
|
E:D601105
|
4.6
|
67.0
|
1.0
|
|
F2
|
E:D601105
|
4.7
|
71.6
|
1.0
|
|
C
|
E:CYS885
|
4.7
|
52.7
|
1.0
|
|
CA
|
E:GLY884
|
4.7
|
67.1
|
1.0
|
|
C11
|
E:D601105
|
4.7
|
55.7
|
1.0
|
|
O3
|
E:GOL1107
|
4.9
|
63.2
|
1.0
|
|
C23
|
E:D601105
|
4.9
|
66.1
|
1.0
|
|
NH2
|
E:ARG935
|
4.9
|
38.5
|
1.0
|
|
O
|
E:GLY883
|
5.0
|
73.8
|
1.0
|
|
N
|
E:MET886
|
5.0
|
50.9
|
1.0
|
|
Fluorine binding site 6 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 6 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:F1105
b:71.6
occ:1.00
|
F2
|
E:D601105
|
0.0
|
71.6
|
1.0
|
|
C16
|
E:D601105
|
1.3
|
66.7
|
1.0
|
|
C17
|
E:D601105
|
2.3
|
62.0
|
1.0
|
|
C15
|
E:D601105
|
2.4
|
70.2
|
1.0
|
|
O3
|
E:D601105
|
2.4
|
71.2
|
1.0
|
|
C14
|
E:D601105
|
2.7
|
71.7
|
1.0
|
|
O2
|
E:GOL1108
|
3.2
|
70.9
|
1.0
|
|
C18
|
E:D601105
|
3.6
|
62.9
|
1.0
|
|
C19
|
E:D601105
|
3.6
|
67.0
|
1.0
|
|
O1
|
E:GOL1108
|
3.6
|
59.8
|
1.0
|
|
C2
|
E:GOL1108
|
3.7
|
73.0
|
1.0
|
|
O1
|
E:D601105
|
3.9
|
59.8
|
1.0
|
|
C1
|
E:GOL1108
|
4.0
|
66.9
|
1.0
|
|
C11
|
E:D601105
|
4.0
|
55.7
|
1.0
|
|
C20
|
E:D601105
|
4.1
|
62.4
|
1.0
|
|
C13
|
E:D601105
|
4.1
|
69.2
|
1.0
|
|
C3
|
E:D601105
|
4.2
|
58.9
|
1.0
|
|
C4
|
E:D601105
|
4.4
|
65.8
|
1.0
|
|
C12
|
E:D601105
|
4.5
|
67.5
|
1.0
|
|
O2
|
E:D601105
|
4.6
|
54.9
|
1.0
|
|
F1
|
E:D601105
|
4.7
|
71.8
|
1.0
|
|
C21
|
E:D601105
|
4.7
|
67.0
|
1.0
|
|
C5
|
E:D601105
|
4.7
|
57.9
|
1.0
|
|
C22
|
E:D601105
|
5.0
|
66.6
|
1.0
|
|
Fluorine binding site 7 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 7 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:F1105
b:69.8
occ:1.00
|
F1
|
G:D601105
|
0.0
|
69.8
|
1.0
|
|
C19
|
G:D601105
|
1.3
|
66.9
|
1.0
|
|
C20
|
G:D601105
|
2.3
|
62.7
|
1.0
|
|
C15
|
G:D601105
|
2.4
|
71.4
|
1.0
|
|
O
|
G:GLY884
|
2.6
|
77.2
|
1.0
|
|
C13
|
G:D601105
|
2.8
|
63.0
|
1.0
|
|
C14
|
G:D601105
|
2.9
|
75.9
|
1.0
|
|
C12
|
G:D601105
|
3.3
|
64.1
|
1.0
|
|
CB
|
G:CYS885
|
3.3
|
62.4
|
1.0
|
|
CA
|
G:CYS885
|
3.4
|
61.4
|
1.0
|
|
C
|
G:GLY884
|
3.5
|
73.2
|
1.0
|
|
C18
|
G:D601105
|
3.6
|
63.2
|
1.0
|
|
C16
|
G:D601105
|
3.6
|
65.8
|
1.0
|
|
N
|
G:CYS885
|
3.8
|
67.6
|
1.0
|
|
O3
|
G:D601105
|
4.0
|
74.2
|
1.0
|
|
C17
|
G:D601105
|
4.1
|
64.6
|
1.0
|
|
SG
|
G:CYS885
|
4.1
|
56.0
|
1.0
|
|
O2
|
G:D601105
|
4.2
|
51.4
|
1.0
|
|
C4
|
G:D601105
|
4.5
|
61.4
|
1.0
|
|
C21
|
G:D601105
|
4.6
|
64.0
|
1.0
|
|
F2
|
G:D601105
|
4.7
|
64.9
|
1.0
|
|
C11
|
G:D601105
|
4.7
|
48.6
|
1.0
|
|
CA
|
G:GLY884
|
4.7
|
71.9
|
1.0
|
|
C
|
G:CYS885
|
4.8
|
57.0
|
1.0
|
|
C23
|
G:D601105
|
4.9
|
64.4
|
1.0
|
|
O
|
G:GLY883
|
4.9
|
83.7
|
1.0
|
|
O1
|
G:GOL1107
|
5.0
|
80.2
|
1.0
|
|
Fluorine binding site 8 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 8 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
G:F1105
b:64.9
occ:1.00
|
F2
|
G:D601105
|
0.0
|
64.9
|
1.0
|
|
C16
|
G:D601105
|
1.3
|
65.8
|
1.0
|
|
C15
|
G:D601105
|
2.3
|
71.4
|
1.0
|
|
C17
|
G:D601105
|
2.3
|
64.6
|
1.0
|
|
O3
|
G:D601105
|
2.4
|
74.2
|
1.0
|
|
C14
|
G:D601105
|
2.7
|
75.9
|
1.0
|
|
O1
|
G:D601105
|
3.5
|
52.3
|
1.0
|
|
C19
|
G:D601105
|
3.6
|
66.9
|
1.0
|
|
C18
|
G:D601105
|
3.6
|
63.2
|
1.0
|
|
O
|
G:HOH1206
|
3.8
|
57.4
|
1.0
|
|
C11
|
G:D601105
|
3.8
|
48.6
|
1.0
|
|
O
|
G:HOH1240
|
4.0
|
72.1
|
1.0
|
|
C20
|
G:D601105
|
4.1
|
62.7
|
1.0
|
|
C3
|
G:D601105
|
4.1
|
55.1
|
1.0
|
|
C13
|
G:D601105
|
4.1
|
63.0
|
1.0
|
|
C4
|
G:D601105
|
4.3
|
61.4
|
1.0
|
|
C12
|
G:D601105
|
4.5
|
64.1
|
1.0
|
|
O2
|
G:D601105
|
4.5
|
51.4
|
1.0
|
|
C5
|
G:D601105
|
4.7
|
62.6
|
1.0
|
|
F1
|
G:D601105
|
4.7
|
69.8
|
1.0
|
|
C21
|
G:D601105
|
4.7
|
64.0
|
1.0
|
|
NH1
|
G:ARG935
|
4.9
|
46.7
|
1.0
|
|
Fluorine binding site 9 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 9 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 9 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:F1105
b:53.2
occ:1.00
|
F1
|
I:D601105
|
0.0
|
53.2
|
1.0
|
|
C19
|
I:D601105
|
1.2
|
45.2
|
1.0
|
|
C20
|
I:D601105
|
2.2
|
43.8
|
1.0
|
|
C15
|
I:D601105
|
2.3
|
51.8
|
1.0
|
|
O
|
I:GLY884
|
2.7
|
69.6
|
1.0
|
|
C14
|
I:D601105
|
2.9
|
57.6
|
1.0
|
|
C13
|
I:D601105
|
2.9
|
58.6
|
1.0
|
|
C15
|
A:D601105
|
3.3
|
51.3
|
1.0
|
|
C14
|
A:D601105
|
3.3
|
57.2
|
1.0
|
|
C19
|
A:D601105
|
3.3
|
51.3
|
1.0
|
|
C12
|
I:D601105
|
3.3
|
57.6
|
1.0
|
|
F1
|
A:D601105
|
3.3
|
58.6
|
1.0
|
|
CB
|
I:CYS885
|
3.5
|
58.6
|
1.0
|
|
O3
|
A:D601105
|
3.5
|
64.2
|
1.0
|
|
C
|
I:GLY884
|
3.5
|
65.0
|
1.0
|
|
C18
|
I:D601105
|
3.5
|
47.5
|
1.0
|
|
C16
|
I:D601105
|
3.5
|
55.8
|
1.0
|
|
CA
|
I:CYS885
|
3.5
|
57.1
|
1.0
|
|
N
|
I:CYS885
|
3.9
|
62.4
|
1.0
|
|
O3
|
I:D601105
|
4.0
|
59.5
|
1.0
|
|
C16
|
A:D601105
|
4.0
|
47.7
|
1.0
|
|
C17
|
I:D601105
|
4.0
|
50.4
|
1.0
|
|
C13
|
A:D601105
|
4.0
|
52.6
|
1.0
|
|
C20
|
A:D601105
|
4.1
|
45.1
|
1.0
|
|
SG
|
I:CYS885
|
4.2
|
59.1
|
1.0
|
|
O2
|
I:D601105
|
4.2
|
46.6
|
1.0
|
|
C4
|
I:D601105
|
4.5
|
53.6
|
1.0
|
|
F2
|
I:D601105
|
4.6
|
62.9
|
1.0
|
|
C21
|
I:D601105
|
4.6
|
50.3
|
1.0
|
|
F2
|
A:D601105
|
4.6
|
55.2
|
1.0
|
|
C11
|
I:D601105
|
4.7
|
51.3
|
1.0
|
|
CA
|
I:GLY884
|
4.7
|
63.2
|
1.0
|
|
C17
|
A:D601105
|
4.7
|
43.4
|
1.0
|
|
C18
|
A:D601105
|
4.7
|
44.3
|
1.0
|
|
C23
|
I:D601105
|
4.9
|
47.7
|
1.0
|
|
O
|
I:GLY883
|
4.9
|
69.3
|
1.0
|
|
C
|
I:CYS885
|
5.0
|
56.0
|
1.0
|
|
Fluorine binding site 10 out
of 12 in 6kc6
Go back to
Fluorine Binding Sites List in 6kc6
Fluorine binding site 10 out
of 12 in the Hoip-HOIPIN8 Complex
 Mono view
 Stereo pair view
|
|
A full contact list of Fluorine with other atoms in the F binding
site number 10 of Hoip-HOIPIN8 Complex within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
I:F1105
b:62.9
occ:1.00
|
F2
|
I:D601105
|
0.0
|
62.9
|
1.0
|
|
C16
|
I:D601105
|
1.3
|
55.8
|
1.0
|
|
C15
|
I:D601105
|
2.3
|
51.8
|
1.0
|
|
C17
|
I:D601105
|
2.3
|
50.4
|
1.0
|
|
O3
|
I:D601105
|
2.4
|
59.5
|
1.0
|
|
C14
|
I:D601105
|
2.6
|
57.6
|
1.0
|
|
O1
|
I:D601105
|
3.2
|
47.6
|
1.0
|
|
C11
|
I:D601105
|
3.5
|
51.3
|
1.0
|
|
O
|
I:HOH1229
|
3.5
|
52.4
|
1.0
|
|
C19
|
I:D601105
|
3.5
|
45.2
|
1.0
|
|
C18
|
I:D601105
|
3.6
|
47.5
|
1.0
|
|
C3
|
I:D601105
|
3.7
|
48.0
|
1.0
|
|
C13
|
I:D601105
|
4.0
|
58.6
|
1.0
|
|
CL
|
A:CL1108
|
4.0
|
90.6
|
1.0
|
|
C20
|
I:D601105
|
4.0
|
43.8
|
1.0
|
|
C4
|
I:D601105
|
4.0
|
53.6
|
1.0
|
|
C5
|
I:D601105
|
4.3
|
45.3
|
1.0
|
|
C12
|
I:D601105
|
4.3
|
57.6
|
1.0
|
|
F1
|
A:D601105
|
4.4
|
58.6
|
1.0
|
|
O2
|
I:D601105
|
4.4
|
46.6
|
1.0
|
|
F1
|
I:D601105
|
4.6
|
53.2
|
1.0
|
|
O
|
A:GLY884
|
4.7
|
74.8
|
1.0
|
|
C21
|
I:D601105
|
4.7
|
50.3
|
1.0
|
|
CA
|
A:GLY884
|
4.8
|
71.8
|
1.0
|
|
C6
|
I:D601105
|
4.9
|
54.4
|
1.0
|
|
O
|
A:GLY883
|
4.9
|
84.7
|
1.0
|
|
C20
|
A:D601105
|
5.0
|
45.1
|
1.0
|
|
Reference:
D.Oikawa,
Y.Sato,
F.Ohtake,
K.Komakura,
K.Hanada,
K.Sugawara,
S.Terawaki,
Y.Mizukami,
H.T.Phuong,
K.Iio,
S.Obika,
M.Fukushi,
T.Irie,
D.Tsuruta,
S.Sakamoto,
K.Tanaka,
Y.Saeki,
S.Fukai,
F.Tokunaga.
Molecular Bases For Hoipins-Mediated Inhibition of Lubac and Innate Immune Responses. Commun Biol V. 3 163 2020.
ISSN: ESSN 2399-3642
PubMed: 32246052
DOI: 10.1038/S42003-020-0882-8
Page generated: Sun Dec 13 12:55:13 2020
|
