Fluorine in PDB 6klk: Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Enzymatic activity of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
All present enzymatic activity of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu:
3.5.2.2;
3.5.2.2;
Protein crystallography data
The structure of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu, PDB code: 6klk
was solved by
Y.H.Huang,
I.C.Chen,
C.Y.Huang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 27.83 / 1.76 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 111.333, 111.333, 159.977, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 18.5 / 21.2 |
Other elements in 6klk:
The structure of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu also contains other interesting chemical elements:
| Zinc | (Zn) | 4 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
(pdb code 6klk). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu, PDB code: 6klk:
In total only one binding site of Fluorine was determined in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu, PDB code: 6klk:
Fluorine binding site 1 out of 1 in 6klk
Go back to
Fluorine Binding Sites List in 6klk
Fluorine binding site 1 out
of 1 in the Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of the Pseudomonas Aeruginosa Dihydropyrimidinase Complexed with 5-Fu within 5.0Å range:
|
Reference:
Y.H.Huang,
Z.J.Ning,
C.Y.Huang.
Crystal Structure of Dihydropyrimidinase in Complex with Anticancer Drug 5-Fluorouracil. Biochem.Biophys.Res.Commun. V. 519 160 2019.
ISSN: ESSN 1090-2104
PubMed: 31481233
DOI: 10.1016/J.BBRC.2019.08.153
Page generated: Sun Dec 13 12:55:33 2020
ISSN: ESSN 1090-2104
PubMed: 31481233
DOI: 10.1016/J.BBRC.2019.08.153
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