Fluorine in PDB 6kuy: Crystal Structure of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist

The structure of Crystal Structure of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist, PDB code: 6kuy was solved by L.Qu, Q.T.Zhou, D.Wu, S.W.Zhao, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.62 / 3.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	71.210, 71.620, 286.250, 90.00, 90.00, 90.00
R / Rfree (%)	26.7 / 29.8

The binding sites of Fluorine atom in the Crystal Structure of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist (pdb code 6kuy). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist, PDB code: 6kuy:

Fluorine binding site 1 out of 1 in the Crystal Structure of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist within 5.0Å range: probe atom residue distance (Å) B Occ A:F1202 b:0.8 occ:1.00 F1 A:E391202 0.0 0.8 1.0 C9 A:E391202 1.4 0.2 1.0 C1 A:E391202 2.4 0.3 1.0 C10 A:E391202 2.4 0.2 1.0 CZ A:PHE391 2.8 0.8 1.0 CB A:CYS117 3.0 0.2 1.0 SG A:CYS117 3.0 0.7 1.0 C6 A:E391202 3.1 0.2 1.0 CB A:SER204 3.4 0.1 1.0 CE2 A:PHE391 3.4 0.1 1.0 OG A:SER204 3.4 0.6 1.0 C14 A:E391202 3.7 0.6 1.0 C12 A:E391202 3.7 0.3 1.0 CE1 A:PHE391 4.0 0.7 1.0 C13 A:E391202 4.1 0.8 1.0 CA A:CYS117 4.2 0.9 1.0 C A:CYS117 4.3 0.5 1.0 O A:VAL114 4.3 0.5 1.0 O A:ASP113 4.4 0.5 1.0 N A:THR118 4.4 0.8 1.0 C5 A:E391202 4.5 0.6 1.0 CA A:VAL114 4.5 0.6 1.0 OG1 A:THR118 4.6 1.0 1.0 CA A:SER204 4.7 0.8 1.0 N1 A:E391202 4.7 0.5 1.0 CD2 A:PHE391 4.8 0.6 1.0 O A:CYS117 4.8 0.1 1.0 C A:SER204 4.9 0.4 1.0 C A:VAL114 4.9 0.4 1.0 N A:CYS117 5.0 0.0 1.0 N A:PHE205 5.0 0.3 1.0

L.Qu, Q.T.Zhou, D.Wu, S.W.Zhao. Crystal Structures of the ALPHA2A Adrenergic Receptor in Complex with A Partial Agonist To Be Published.