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Fluorine in PDB 6mny: Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9AEnzymatic activity of Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A
All present enzymatic activity of Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A:
2.7.10.2; Protein crystallography data
The structure of Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A, PDB code: 6mny
was solved by
S.Han,
N.Caspers,
J.O.Ohren,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A
(pdb code 6mny). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A, PDB code: 6mny: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 6mnyGo back to Fluorine Binding Sites List in 6mny
Fluorine binding site 1 out
of 2 in the Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 6mnyGo back to Fluorine Binding Sites List in 6mny
Fluorine binding site 2 out
of 2 in the Crystal Structure of Mouse Btk Kinase Domain in Complex with Compound 9A
Mono view Stereo pair view
Reference:
M.E.Schnute,
S.E.Benoit,
I.P.Buchler,
N.Caspers,
M.L.Grapperhaus,
S.Han,
R.Hotchandani,
N.Huang,
R.O.Hughes,
B.M.Juba,
K.H.Kim,
E.Liu,
E.Mccarthy,
D.Messing,
J.S.Miyashiro,
S.Mohan,
T.N.O'connell,
J.F.Ohren,
M.D.Parikh,
M.Schmidt,
S.R.Selness,
J.R.Springer,
V.Thanabal,
J.I.Trujillo,
D.P.Walker,
Z.K.Wan,
J.M.Withka,
A.J.Wittwer,
N.L.Wood,
L.Xing,
C.W.Zapf,
J.Douhan Iii.
Aminopyrazole Carboxamide Bruton'S Tyrosine Kinase Inhibitors. Irreversible to Reversible Covalent Reactive Group Tuning. Acs Med Chem Lett V. 10 80 2019.
Page generated: Sun Dec 13 12:58:55 2020
ISSN: ISSN 1948-5875 PubMed: 30655951 DOI: 10.1021/ACSMEDCHEMLETT.8B00461 |
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