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Fluorine in PDB 6mu8: Crystal Structure of Hiv-1 BG505 Sosip.664 Prefusion Env Trimer Bound to Small Molecule Hiv-1 Entry Inhibitor Bms-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 AngstromProtein crystallography data
The structure of Crystal Structure of Hiv-1 BG505 Sosip.664 Prefusion Env Trimer Bound to Small Molecule Hiv-1 Entry Inhibitor Bms-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom, PDB code: 6mu8
was solved by
Y.-T.Lai,
P.D.Kwong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6mu8:
The structure of Crystal Structure of Hiv-1 BG505 Sosip.664 Prefusion Env Trimer Bound to Small Molecule Hiv-1 Entry Inhibitor Bms-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Hiv-1 BG505 Sosip.664 Prefusion Env Trimer Bound to Small Molecule Hiv-1 Entry Inhibitor Bms-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
(pdb code 6mu8). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Hiv-1 BG505 Sosip.664 Prefusion Env Trimer Bound to Small Molecule Hiv-1 Entry Inhibitor Bms-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom, PDB code: 6mu8: Fluorine binding site 1 out of 1 in 6mu8Go back to Fluorine Binding Sites List in 6mu8
Fluorine binding site 1 out
of 1 in the Crystal Structure of Hiv-1 BG505 Sosip.664 Prefusion Env Trimer Bound to Small Molecule Hiv-1 Entry Inhibitor Bms-386150 in Complex with Human Antibodies 3H109L and 35O22 at 3.5 Angstrom
Mono view Stereo pair view
Reference:
Y.T.Lai,
T.Wang,
S.O'dell,
M.K.Louder,
A.Schon,
C.S.F.Cheung,
G.Y.Chuang,
A.Druz,
B.Lin,
K.Mckee,
D.Peng,
Y.Yang,
B.Zhang,
A.Herschhorn,
J.Sodroski,
R.T.Bailer,
N.A.Doria-Rose,
J.R.Mascola,
D.R.Langley,
P.D.Kwong.
Lattice Engineering Enables Definition of Molecular Features Allowing For Potent Small-Molecule Inhibition of Hiv-1 Entry. Nat Commun V. 10 47 2019.
Page generated: Sun Dec 13 12:59:01 2020
ISSN: ESSN 2041-1723 PubMed: 30604750 DOI: 10.1038/S41467-018-07851-1 |
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