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Fluorine in PDB 6n6o: Crystal Structure of the Human Ttk in Complex with An InhibitorEnzymatic activity of Crystal Structure of the Human Ttk in Complex with An Inhibitor
All present enzymatic activity of Crystal Structure of the Human Ttk in Complex with An Inhibitor:
2.7.12.1; Protein crystallography data
The structure of Crystal Structure of the Human Ttk in Complex with An Inhibitor, PDB code: 6n6o
was solved by
G.Fenalti,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6n6o:
The structure of Crystal Structure of the Human Ttk in Complex with An Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Human Ttk in Complex with An Inhibitor
(pdb code 6n6o). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structure of the Human Ttk in Complex with An Inhibitor, PDB code: 6n6o: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 6n6oGo back to Fluorine Binding Sites List in 6n6o
Fluorine binding site 1 out
of 3 in the Crystal Structure of the Human Ttk in Complex with An Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 6n6oGo back to Fluorine Binding Sites List in 6n6o
Fluorine binding site 2 out
of 3 in the Crystal Structure of the Human Ttk in Complex with An Inhibitor
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 6n6oGo back to Fluorine Binding Sites List in 6n6o
Fluorine binding site 3 out
of 3 in the Crystal Structure of the Human Ttk in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
J.R.Riggs,
J.Elsner,
D.Cashion,
D.Robinson,
L.Tehrani,
M.Nagy,
K.E.Fultz,
R.Krishna Narla,
X.Peng,
T.Tran,
A.Kulkarni,
S.Bahmanyar,
K.Condroski,
B.Pagarigan,
G.Fenalti,
L.Lebrun,
K.Leftheris,
D.Zhu,
J.F.Boylan.
Design and Optimization Leading to An Orally Active Ttk Protein Kinase Inhibitor with Robust Single Agent Efficacy. J.Med.Chem. V. 62 4401 2019.
Page generated: Sun Dec 13 12:59:30 2020
ISSN: ISSN 0022-2623 PubMed: 30998356 DOI: 10.1021/ACS.JMEDCHEM.8B01869 |
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