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Fluorine in PDB 6ncj: Structure of Hiv-1 Integrase with Potent 5,6,7,8-Tetrahydro-1,6- Naphthyridine Derivatives Allosteric Site InhibitorsProtein crystallography data
The structure of Structure of Hiv-1 Integrase with Potent 5,6,7,8-Tetrahydro-1,6- Naphthyridine Derivatives Allosteric Site Inhibitors, PDB code: 6ncj
was solved by
R.T.Nolte,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure of Hiv-1 Integrase with Potent 5,6,7,8-Tetrahydro-1,6- Naphthyridine Derivatives Allosteric Site Inhibitors
(pdb code 6ncj). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure of Hiv-1 Integrase with Potent 5,6,7,8-Tetrahydro-1,6- Naphthyridine Derivatives Allosteric Site Inhibitors, PDB code: 6ncj: Fluorine binding site 1 out of 1 in 6ncjGo back to Fluorine Binding Sites List in 6ncj
Fluorine binding site 1 out
of 1 in the Structure of Hiv-1 Integrase with Potent 5,6,7,8-Tetrahydro-1,6- Naphthyridine Derivatives Allosteric Site Inhibitors
Mono view Stereo pair view
Reference:
K.M.Peese,
C.W.Allard,
T.Connolly,
B.L.Johnson,
C.Li,
M.Patel,
M.E.Sorensen,
M.A.Walker,
N.A.Meanwell,
B.Mcauliffe,
B.Minassian,
M.Krystal,
D.D.Parker,
H.A.Lewis,
K.Kish,
P.Zhang,
R.T.Nolte,
J.Simmermacher,
S.Jenkins,
C.Cianci,
B.N.Naidu.
5,6,7,8-Tetrahydro-1,6-Naphthyridine Derivatives As Potent Hiv-1-Integrase-Allosteric-Site Inhibitors. J. Med. Chem. V. 62 1348 2019.
Page generated: Sun Dec 13 12:59:35 2020
ISSN: ISSN 1520-4804 PubMed: 30609350 DOI: 10.1021/ACS.JMEDCHEM.8B01473 |
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