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Atomistry » Fluorine » PDB 6n4e-6ngp » 6nfy | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 6n4e-6ngp » 6nfy » |
Fluorine in PDB 6nfy: Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State.Enzymatic activity of Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State.
All present enzymatic activity of Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State.:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State., PDB code: 6nfy
was solved by
E.Johnson,
M.Mctigue,
C.N.Cronin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State.
(pdb code 6nfy). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State., PDB code: 6nfy: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 6nfyGo back to Fluorine Binding Sites List in 6nfy
Fluorine binding site 1 out
of 2 in the Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State.
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 6nfyGo back to Fluorine Binding Sites List in 6nfy
Fluorine binding site 2 out
of 2 in the Crystal Structure of Nonphosphorylated, HPK1 Kinase Domain in Complex with Sunitinib in the Inactive State.
Mono view Stereo pair view
Reference:
E.Johnson,
M.Mctigue,
R.A.Gallego,
T.W.Johnson,
S.Timofeevski,
M.Maestre,
T.S.Fisher,
R.Kania,
S.Sawasdikosol,
S.Burakoff,
C.N.Cronin.
Multiple Conformational States of the HPK1 Kinase Domain in Complex with Sunitinib Reveal the Structural Changes Accompanying HPK1 Trans-Regulation. J.Biol.Chem. V. 294 9029 2019.
Page generated: Thu Aug 1 22:32:37 2024
ISSN: ESSN 1083-351X PubMed: 31018963 DOI: 10.1074/JBC.AC119.007466 |
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