Fluorine in PDB 6nm0: Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
Enzymatic activity of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
All present enzymatic activity of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines:
4.2.1.1;
4.2.1.1;
Protein crystallography data
The structure of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines, PDB code: 6nm0
was solved by
S.Singh,
R.Mckenna,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.63 / 1.44 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 42.562, 41.529, 72.027, 90.00, 104.27, 90.00 |
| R / Rfree (%) | 16.6 / 18 |
Other elements in 6nm0:
The structure of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines also contains other interesting chemical elements:
| Zinc | (Zn) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
(pdb code 6nm0). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines, PDB code: 6nm0:
Jump to Fluorine binding site number: 1; 2;
In total 2 binding sites of Fluorine where determined in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines, PDB code: 6nm0:
Jump to Fluorine binding site number: 1; 2;
Fluorine binding site 1 out of 2 in 6nm0
Go back to
Fluorine Binding Sites List in 6nm0
Fluorine binding site 1 out
of 2 in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines within 5.0Å range:
|
Fluorine binding site 2 out of 2 in 6nm0
Go back to
Fluorine Binding Sites List in 6nm0
Fluorine binding site 2 out
of 2 in the Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines within 5.0Å range:
|
Reference:
S.Singh,
R.Mckenna,
M.Y.Mboge,
A.Wolff,
S.C.Clark,
T.Chingkuang,
C.T.Supuran,
Z.Zhang,
S.C.Frost.
Selective Inhibition of Carbonic Anhydrase IX Activity, Using Compound Slc-149, Displays Limited Anticancer Effects in Breast Cancer Cell Lines To Be Published.
Page generated: Sun Dec 13 13:00:57 2020
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